My career dreams, of staying at headquarters and moving to upper management as time went on, were dashed by my diagnosis with inflammatory breast cancer in 2007, a cancer that became metastatic, residing in my spine, neck, hips, ribs, and leg in 2010. Now, I am in chemotherapy for the rest of my life, which is essential for me to live. I can't work an 8-5 job anymore. But that doesn't mean that I have to give up. Instead, I forged my own path, bidding on work in industry and holding NASA research grants. I have created a career that allows the necessary time for treatment, recovery, physical therapy, and real time with my children. Will I be a mission PI? No. But I'm still able to contribute to the field despite my physical limitations. I think that's the advice. Know what is important to you, and find a way to make that happen.