Rodent Research Stories

NASA’s BioNutrients series of experiments is testing ways to use microorganisms to make nutrients that will be needed for human health during future long-duration deep space exploration missions. Some vital nutrients lack the shelf-life needed to span multi-year human missions,…

Risk is inherent in human spaceflight. However, specific risks can and should be understood, managed, and mitigated to reduce threats posed to astronauts. Risk management in the context of human spaceflight can be viewed as a trade-based system. The relevant…

New spacecraft that will transport crews to the Lunar and Martian surfaces and return them to Earth may have diverse landing modalities which will function in different landing environments. Additionally, the crew may be deconditioned on landing, impacting their ability…

It is important to protect humans from unintended electrical current flow during spaceflight. The thresholds for contact electrical shock are well established, and standards and requirements exist that minimize the probability of contact electrical shock. Current thresholds were chosen (vs.…

Exposure to the altered gravity in the spaceflight environment may cause physiological changes. One of these changes is the inability to completely empty the bladder or urinary retention. Causes of urinary retention in the early phases of flight include altered…

Safe, breathable air is essential for crew health. Human spaceflight has involved toxicological events ranging in severity from trivial to life-threatening. Toxic exposure to chemical contaminants can originate from environmental system leaks, payload leaks, pyrolysis of polymeric materials, off-gassing of…

Exposure to altered gravity can cause ocular and brain structural changes to develop during spaceflight; these changes could lead to vision alterations, cognitive effects, or other deleterious health effects. SANS is a syndrome unique to humans that fly in space,…

Exposure to microgravity induces bone atrophy/bone loss which increases circulating calcium, impacting the renal stone risk. Risk mitigation strategies including exercise and hydration are well-defined although the ability to treat a renal stone during exploration missions is not yet available.…

Exposure to the microgravity environment causes muscle size, strength, and endurance to decline. Based on ISS data, if crew adhere to the exercise schedule and have access to adequate exercise countermeasure systems then on average, they return with minimal losses…