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OSDR Enabled Publications – 130
| Title | Description | Datasets |
|---|---|---|
| Spatially Resolved Transcriptomic Response of Human Deltoid Skin to Microgravity: A Differential Expression Analysis Using the OSD-574 Dataset | Sahu B, Sahu I (2025). Spatially Resolved Transcriptomic Response of Human Deltoid Skin to Microgravity: A Differential Expression Analysis Using the OSD-574 Dataset, Research Square. https://doi.org/10.21203/rs.3.rs-7394662/v1 | OSD-574 |
| The evolution of superbugs in space: a genomic perspective on pathogens in the International Space Station environment | Pearl S, Kumar H, Vijayakumar S, Basu S, Ramaiah S, Anbarasu A (2025). The evolution of superbugs in space: a genomic perspective on pathogens in the International Space Station environment, Journal of Genetic Engineering and Biotechnology. doi: 10.1016/j.jgeb.2025.100536 | |
| Genomic description of Microbacterium mcarthurae sp. nov., a bacterium collected from the International Space Station that exhibits unique antimicrobial-resistant and virulent phenotype | Hill M S, Minnis V R, Simpson A C, Garcia M C, Bone D, Chung R K, Rushton E, et al (2025). Genomic description of Microbacterium mcarthurae sp. nov., a bacterium collected from the International Space Station that exhibits unique antimicrobial-resistant and virulent phenotype, Environmental Microbiology. doi: 10.1128/msystems.00537-25 | OSD-69, OSD-252 |
| Feeding the cosmos: tackling personalized space nutrition and the leaky gut challenge | Barcenilla B B, Rivero R, Lynch A, Cromer W, Gong J, Hrandi B, Stegmann M, et al, (2025). Feeding the cosmos: tackling personalized space nutrition and the leaky gut challenge, npj microgravity. https://doi.org/10.1038/s41526-025-00490-z | OSD-269, OSD-796, OSD-569, OSD-570, OSD-571, OSD-575 |
| Prediction of Cerebrospinal Fluid (CSF) Pressure with Generative Adversarial Network Synthetic Plasma-CSF Biomarker Pairing | Paladugu P, Kumar R, Yelamanchi J, Waisberg E, Ong J, Masalkhi M, Gowda C, et al, (2025). Prediction of Cerebrospinal Fluid (CSF) Pressure with Generative Adversarial Network Synthetic Plasma-CSF Biomarker Pairing, Neuroinformatics. https://doi.org/10.1007/s12021-025-09729-2 | OSD-363, OSD-364 |
| Deep Cross-Organism Generalization of the Physiological Effects of Spaceflight from Mammalian Model Organisms to Humans | Adamopoulos K I, Sanders L M, Hoarfrost A, Costes S V, (2025). Deep Cross-Organism Generalization of the Physiological Effects of Spaceflight from Mammalian Model Organisms to Humans, Sciendo. DOI: 10.2478/gsr-2025-0003 | OSD-111, OSD-228, OSD-227, OSD-135, OSD-21, OSD-51, OSD-195, OSD-370 |
| Plasticity of Gene Expression in Spaceflight and Postflight in Relation to Cardiovascular Disease: Mechanisms and Candidate Repurposed Drugs | Bourdakou M M, Loizidou E M, Spyrou G M, (2025). Plasticity of Gene Expression in Spaceflight and Postflight in Relation to Cardiovascular Disease: Mechanisms and Candidate Repurposed Drugs, Proteomics. https://doi.org/10.1002/pmic.202400241 | OSD-258 |
| Spaceflight causes strain-dependent gene expression changes in the kidneys of mice | Finch R H, Vitry G, Siew K, Walsh S B, Beheshti A, Hardiman G, da Silveira W A. Spaceflight causes strain-dependent gene expression changes in the kidneys of mice, Microgravity. https://doi.org/10.1038/s41526-025-00465-0 | OSD-102, OSD-163 |
| Effects of Space Flight on Inflammasome Activation in the Brain of Mice | Roy U, Hadad R, Rodriguez A A, Saju A, Roy D, Gil M, Keane R W, et al (2025). Effects of Space Flight on Inflammasome Activation in the Brain of Mice, Cells. https://doi.org/10.3390/cells14060417 | OSD-738, OSD-751, OSD-752, EDA |
| Highly Effective Batch Effect Correction Method for RNA-seq Count Data | Zhang X, (2024). Highly Effective Batch Effect Correction Method for RNA-seq Count Data, Computational and Sturctural Biotechnology Journal. https://doi.org/10.1016/j.csbj.2024.12.010 | OSD-48, OSD-137, OSD-242 |
| Machine learning ensemble identifies distinct age-related response to spaceflight in mammary tissue | Casaletto J A, Zhao T, Yeung J, Ansari A, Raj A, Mishra A, Fry A, et al, (2025). Machine learning ensemble identifies distinct age-related response to spaceflight in mammary tissue, bioRxiv. https://doi.org/10.1101/2025.02.17.638732 | OSD-511 |
| Behavioral and multiomics analysis of 3D clinostat simulated microgravity effect in mice focusing on the central nervous system | Zhou L, Song C, Yang H, Zhao L, Li X, Sun X, Gao K, et al, (2025). Behavioral and multiomics analysis of 3D clinostat simulated microgravity effect in mice focusing on the central nervous system, Scientific Reports. https://doi.org/10.1038/s41598-025-90212-y | OSD-32, OSD-352 |
| Exploring the Impact of Microgravity on Gene Expression: Dysregulated Pathways and Candidate Repurposed Drugs | Galcenko K, Bourdakou M M, Spyrou G M, (2025). Exploring the Impact of Microgravity on Gene Expression: Dysregulated Pathways and Candidate Repurposed Drugs, International Journal of Molecular Sciences. https://doi.org/10.3390/ijms26031287 | OSD-125, OSD-172, OSD-188, OSD-297 |
| Integrated spaceflight transcriptomic analyses and simulated space experiments reveal key molecular features and functional changes driven by space stressors in space-flown C. elegans | Zhang G, Zhao L, Li Z, Sun Y, (2025). Integrated spaceflight transcriptomic analyses and simulated space experiments reveal key molecular features and functional changes driven by space stressors in space-flown C. elegans, Life Sciences in Space Research. https://doi.org/10.1016/j.lssr.2024.11.004 | OSD-41, OSD-42, OSD-112, OSD-113 |
| Space exploration and risk of Parkinson’s disease: a perspective review | Ali N, Beheshti A, Hampkian G, (2025). Space exploration and risk of Parkinson’s disease: a perspective review, npj microgravity. https://doi.org/10.1038/s41526-024-00457-6 | OSD-13, OSD-52, OSD-114, OSD-174 |
| Bridging Earth and Space: A Flexible and Resilient Federated Learning Framework Deployed on the International Space Station | Casaletto J A, Foley P, Fernandez M, Sanders L M, Scott R T, Ranjan S, Jain S, et al (2025). Bridging Earth and Space: A Flexible and Resilient Federated Learning Framework Deployed on the International Space Station, bioRxiv. doi: https://doi.org/10.1101/2025.01.14.633017 | OSD-435 |
| Non-DNA radiosensitive targets that initiate persistent behavioral deficits in rats exposed to space radiation | Straume T, Mora A M, Brown J B, Bansal I, Rabin B M, Braby L A, Wyrobek A J, (2024). Non-DNA radiosensitive targets that initiate persistent behavioral deficits in rats exposed to space radiation, Life Sciences in Space Research. https://doi.org/10.1016/j.lssr.2024.12.003 | OSD-490, OSD-492, OSD-495, OSD-626 |
| Analyzing the relationship between gene expression and phenotype in space-flown mice using a causal inference machine learning ensemble | Casaletto J A, Scott R T, Myrick M, Mackintosh G, Chok H, Saravia-Butler A, Hoarfrost A, et atl (2024). Analyzing the relationship between gene expression and phenotype in space-flown mice using a causal inference machine learning ensemble, Scientific Reports. https://doi.org/10.1038/s41598-024-81394-y | OSD-47, OSD-48, OSD-137, OSD-168 |
| Pharmacogenomics Guided Spaceflight: the intersection between space-flown drugs and space genes | Nelson T M, Rose J K, Walter C E, Cervantes-Navarro G L, Schmidt C M, Lin R, Alexander E, et al, (2024). Pharmacogenomics Guided Spaceflight: the intersection between space-flown drugs and space genes, bioRxiv. doi: https://doi.org/10.1101/2024.01.16.575951 | OSD-258 |
| Spaceflight Shifts in Community rRNA Copy Number in the Salivary Microbiome of Astronauts | Williamson M R, (2024). Spaceflight Shifts in Community rRNA Copy Number in the Salivary Microbiome of Astronauts, bioRxiv. doi: https://doi.org/10.1101/2024.06.12.598653 | OSD-280 |
| Feature Selection in High-Dimensional Space with Applications to Gene Expression Data | Pantha N, Ramasubramanian M, Gurung I, Maskey M, Sanders L M, Casaletto J, Costes S V, (2024). Feature Selection in High-Dimensional Space with Applications to Gene Expression Data. DOI: 10.1109/SOUTHEASTCON52093.2024.10500057 | OSD-47, OSD-48, OSD-137, OSD-168, OSD-173, OSD-242, OSD-245 |
| A Machine Learning Model of Perturb-Seq Data for Use in Space Flight Gene Expression Profile Analysis | Johnson L, Casaletto J, Costes S, Proctor C, Sanders L, (2024). A Machine Learning Model of Perturb-Seq Data for Use in Space Flight Gene Expression Profile Analysis, bioRxiv. doi: https://doi.org/10.1101/2024.11.28.625741 | OSD-91 |
| GLARE: Discovering Hidden Patterns in Spaceflight Transcriptome Using Representation Learning | Seo D, Strickland H F, Zhour M, Barker R, Ferl R J, Paul A L, Gilroy S, (2024). GLARE: Discovering Hidden Patterns in Spaceflight Transcriptome Using Representation Learning, bioRxiv. doi: https://doi.org/10.1101/2024.06.04.597470 | OSD-120 |
| Microarray Gene Expression Analysis Using QR Decomposition, Machine Learning Algorithm, And Statistical Tool | Ali M, Choudhary J, (2024). Microarray Gene Expression Analysis Using QR Decomposition, Machine Learning Algorithm, And Statistical Tool, 10th International Conference on Advanced Computing and Communications Systems (ICACCS). DOI: 10.1109/ICACCS60874.2024.10717230 | |
| NASA open science data repository: open science for life in space | Gebre S G, Scott R T, Saravia-Butler A M, Lopez D K, Sanders L M, Costes S V (2024). NASA open science data repository: open science for life in space, Nucleic Acids Research. https://doi.org/10.1093/nar/gkae1116 | |
| Spaceflight disrupts gene expression of estrogen signaling in rodent mammary tissue | Arnold C, Casaletto J, Heller P (2024). Spaceflight disrupts gene expression of estrogen signaling in rodent mammary tissue, Medical Research Archives. https://doi.org/10.18103/mra.v12i3.5220 | OSD-511 |
| Systemic Genome Correlation Loss as a Central Characteristic of Spaceflight | Sakharkar A, Lukong E, Sanders L M, Costes S V, Taghibiglou C, Yang J, (2024). Systemic Genome Correlation Loss as a Central Characteristic of Spaceflight, bioRxiv. https://doi.org/10.1101/2024.01.24.577100 | OSD-118, OSD-174, OSD-258, OSD-323, OSD-431 |
| Light has a principal role in the physiological adaptation of plants to the spaceflight environment | Zhou M, Paul A-L, Ferl R, (2024). Light has a principal role in the physiological adaptation of plants to the spaceflight environment, ResearchSquare. https://doi.org/10.21203/rs.3.rs-4085160/v1 | OSD-678, OSD-120 |
| To boldly go where no microRNAs have gone before: Spaceflight impact on risk for small-for-gestational-age infant | Corti G, Kim J, Enguita F J, Guarnieri J W, Grossman L I, Costes S V, Fuentealba M, et al, (2024). To boldly go where no microRNAs have gone before: Spaceflight impact on risk for small-for-gestational-age infant, communications biology. https://doi.org/10.1038/s42003-024-06944-6 | OSD-55, OSD-336 |
| Unveiling Parkinson’s Disease-like Changes Triggered by Spaceflight | Ali N, Beheshti A, Hampkian G, (2024). Unveiling Parkinson’s Disease-like Changes Triggered by Spaceflight, arxiv. https://arxiv.org/pdf/2408.15021 | OSD-13, OSD-52, OSD-114, OSD-174 |
| Metabolic Stress In Space: ROS-Induced Mutations In Mice Hint At A New Path To Cancer | Stolc V, Karhanek M, Freund F, Griko Y, Loftus D J, Ohayon M M, (2024). Metabolic Stress In Space: ROS-Induced Mutations In Mice Hint At A New Path To Cancer, Redox Biology. https://doi.org/10.1016/j.redox.2024.103398 | OSD-102, OSD-103, OSD-137, OSD-162 |
| RadLab: An open science resource for radiation studies relevant to human spaceflight | Grigorev K A, Miller J, Narici L, Costes S V, (2024). RadLab: An open science resource for radiation studies relevant to human spaceflight, Life Sciences in Space Research. https://doi.org/10.1016/j.lssr.2024.10.001 | |
| Mission SpaceX CRS-19 RRRM-1 Space Flight Induced Skin Genomic Plasticity via an Epigenetic Trigger | Singh K, Verma P, Srivastava R, Rustagi Y, Kumar M, Verma S S, Mohanty S, et al, (2024). Mission SpaceX CRS-19 RRRM-1 Space Flight Induced Skin Genomic Plasticity via an Epigenetic Trigger, iScience. https://doi.org/10.1016/j.isci.2024.111382 | OSD-239 |
| Profiling muscle transcriptome in mice exposed to microgravity using gene set enrichment analysis | Oommen A M, Stafford P, Joshi L, (2024). Profiling muscle transcriptome in mice exposed to microgravity using gene set enrichment analysis, npj microgravity. https://doi.org/10.1038/s41526-024-00434-z | OSD-99, OSD-101, OSD-103, OSD-104, OSD-105, OSD-111, OSD-135, OSD-21 |
| Space radiation measurements during the Artemis I lunar mission | George S P, Gaza R, Matthia D, Laramore D, Lehti J, Campbell-Ricketss T, Kroupa M, et al, (2024). Space radiation measurements during the Artemis I lunar mission, Nature. https://doi.org/10.1038/s41586-024-07927-7 | |
| Celebrating 30 years of access to NASA Space Life Sciences data | Sanders L M, Lopez D K, Wood A E, Scott R T, Gebre S G, Saravia-Butler A M, and Costes S V, (2024). Celebrating 30 years of access to NASA Space Life Sciences data, GigaScience. DOI: 10.1093/gigascience/giae066 | |
| Transcriptional response of Arabidopsis thaliana’s root-tip to spaceflight | Shahbazi M, Rutter L A, Barker R, (2024). Transcriptional response of Arabidopsis thaliana’s root-tip to spaceflight, Plant Molecular Biology. DOI: 10.1007/s11103-024-01478-1 | OSD-120 |
| Spaceflight alters host-gut microbiota interactions | Gonzalez E, Lee M D, Tierney B T, Lipieta N, Flores P, Mishra M, Beckett L, et al, (2024). Spaceflight alters host-gut microbiota interactions, npj biofilms and microbiomes. https://doi.org/10.1038/s41522-024-00545-1 | OSD-245, OSD-247, OSD-249 |
| Integrated analysis of miRNAome and transcriptome reveals that microgravity induces the alterations of critical functional gene modules via the regulation of miRNAs in short-term space-flown C. elegans | He X, Zhao L, Huang B, Zhang G, Lu Y, Mi D, Sun Y, (2024). Integrated analysis of miRNAome and transcriptome reveals that microgravity induces the alterations of critical functional gene modules via the regulation of miRNAs in short-term space-flown C. elegans, Life Sciences in Space Research. https://doi.org/10.1016/j.lssr.2024.07.001 | OSD-75, OSD-112 |
| Fungal diversity differences in the indoor dust microbiome from built environments on earth and in space | Nastasi M, Haines S R, Bope A, Meyer M E, Horack J M, Dannemiller K C, (2024). Fungal diversity in the indoor dust microbiome from built environments on earth and in space, Scientific Reports. doi: 10.1038/s41598-024-62191-z | OSD-694 |
| Aging and putative frailty biomarkers are altered by spaceflight | Camera A, Tabetah M, Castaneda V, Kim J, Galsinh A S, Haro-Vinueza A, Salinas I, et al, (2024). Aging and putative frailty biomarkers are altered by spaceflight, Scientific Reports. doi: 10.1038/s41598-024-57948-5 | OSD-21, OSD-52, OSD-99, OSD-101, OSD-103, OSD-104, OSD-105, OSD-195, OSD-202 |
| Cosmic kidney disease: An integrated pan-omic, physiological and morphological study into spaceflight-induced renal dysfunction | Siew K, Nestler K A, Nelson C, D’Ambrosio V, Zhong C, Li Z, Grillo A, et al, (2024). Cosmic kidney disease: An integrated pan-omic, physiological and morphological study into spaceflight-induced renal dysfunction, Nature Communications. doi: 10.1038/s41467-024-49212-1 | OSD-72, OSD-102, OSD-163, OSD-212, OSD-249, OSD-250, OSD-253, OSD-336, OSD-342, OSD-457, OSD-462, OSD-465, OSD-466, OSD-513, OSD-530, OSD-532, OSD-571, OSD-575, OSD-706, OSD-707, OSD-708, OSD-709, OSD-710, OSD-712 |
| Harmonizing heterogeneous transcriptomics datasets for machine learning-based analysis to identify spaceflown murine liver-specific changes | Ilangovan H, Kothiyal P, Hoadley K A, Elgart R, Eley G, Eslami P, (2024). Harmonizing heterogeneous transcriptomics datasets for machine learning-based analysis to identify spaceflown murine liver-specific changes, npj microgravity. doi: 10.1038/s41526-024-00379-3 | OSD-47, OSD-168, OSD-242, OSD-245, OSD-379 |
| Secretome profiling reveals acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight | Houerbi N, Kim J, Overbey E G, Batra R, Schweickart A, Patras L, Lucotti S, et al, (2024). Secretome profiling reveals acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight, Communications Medicine. doi: 10.1038/s41467-024-48841-w | OSD-530, OSD-569, OSD-571 |
| Single-cell analysis identifies conserved features of immune dysfunction in simulated microgravity and spaceflight | Wu F, Du J, Overbey E, Kim J, Makhijani P, Martin N, Lerner C A, et al, (2024). Single-cell analysis identifies conserved features of immune dysfunction in simulated microgravity and spaceflight, Nature Communications. doi: 10.1038/s41467-023-42013-y | OSD-420 |
| Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight | Kim J, Tierney B T, Overbey E G, Dantas E, Fuentealba M, Park J, Narayanan S A, et al, (2024). Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight, Nature Communications. doi: 10.1038/s41467-024-49211-2 | OSD-530, OSD-570, OSD-575 |
| Space radiation damage rescued by inhibition of key spaceflight-associated miRNAs | McDonald J T, Kim J, Farmerie L, Johnson M L, Trovao N S, Arif S, Siew K, et al, (2024). Space radiation damage rescued by inhibition of key spaceflight-associated miRNAs, Nature Communications. doi: 10.1038/s41467-024-48920-y | OSD-334, OSD-335, OSD-336, OSD-337, OSD-530, OSD-570, OSD-577 |
| Spaceflight induces changes in gene expression profiles linked to insulin and estrogen | Mathyk B A, Tabetah M, Karim R, Zaksas V, Kim J, Anu R I, Muratani M, et al, (2024). Spaceflight induces changes in gene expression profiles linked to insulin and estrogen, Communications Biology. doi: 10.1038/s42003-023-05213-2 | OSD-48, OSD-98, OSD-99, OSD-100, OSD-101, OSD-102, OSD-103, OSD-104, OSD-105, OSD-168, OSD-238, OSD-239, OSD-240, OSD-241, OSD-254, OSD-530 |
| Spatially resolved multiomics on the neuronal effects induced by spaceflight in mice | Masarapu Y, Cekanaviciute E, Andrusivova Z, Westholm J O, Bjorklund A, Fallegger R, Badia-i-Mompel P, et al (2024). Spatially resolved multiomics on the neuronal effects <mark>induced by spaceflight in mice, Nature C<mark>ommunications.m> doi: 10.1038/s41467-024-48916-8 | GLDS-352 |
| Spatiotemporal expression and control of haemoglobin in space | Borg J, Loy C, Kim J, Buhagiar A, Chin C, Damle N, De Vlaminck I, et al, (2024). Spatiotemporal expression and control of haemoglobin in space, Nature Communications. doi: 10.1038/s41467-024-49289-8 | OSD-530, OSD-570 |
| Transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology | Cope H, Elsborg J, Demharter S, McDonald J T, Wernecke C, Parthasarathy H, Unadkat H, et al, (2024). Transcriptomics analysis reveals molecular alterations underpinning spaceflight dermatology, Communications Medicine. doi: 10.1038/s43856-024-00532-9 | OSD-238, OSD-239, OSD-240, OSD-241, OSD-254 |
| Citizen Science Approach for Searching and Curating Literature on the Effects of Spaceflight on Cardiovascular Outcomes in Rodents and Humans | Neset M, Scott R T, Narayaan S A, Komarova S V, (2024). Citizen Science Approach for Searching and Curating Literature on the Effects of Spaceflight on Cardiovascular Outcomes in Rodents and Humans, Citizen Science: Theory and Practice. DOI: 10.5334/cstp.687 | |
| Altered quorum sensing and physiology of Staphylococcus aureus during spaceflight detected by multi-omics data analysis | Hauserman M R, Ferraro M J, Carroll R K, Rice K C, (2024). Altered quorum sensing and physiology of Staphylococcus aureus during spaceflight detected by multi-omics data analysis, npj Microgravity. doi: 10.1038/s41526-023-00343-7 | OSD-145, OSD-500 |
| Analysis of the influence of microgravity and space radiation on astronauts’ gene expression: An approach using quantum simulations and fuzzy logic | Vargas Cruz M A, (2024). Analysis of the influence of microgravity and space radiation on astronauts’ gene expression: An approach using quantum simulations and fuzzy logic, Precis. Nanomed. doi.org/10.33218/001c.117460 | OSD-530 |
| Chromosomal positioning and epigenetic architecture influence DNA methylation patterns triggered by galactic cosmic radiation | Perdyan A, Jakalski M, Horbacz M, Beheshti A, Mieczkowski J, (2024). Chromosomal positioning and epigenetic architecture influence DNA methylation patterns triggered by galactic cosmic radiation, Scientific Reports. doi: 10.1038/s41598-024-51756-7 | OSD-80, OSD-109, OSD-117, OSD-159, OSD-203, OSD-294, OSD-317, OSD-530 |
| Diacylglycerol kinase is downregulated in the Drosophila Seizure Mutant during Spaceflight | Samson F, Bhat A, Sayyah Z, Reinsch S, Blaber E, (2024). Diacylglycerol kinase is downregulated in the Drosophila Seizure Mutant during Spaceflight, Gravitational and Space Research. DOI: 10.2478/gsr-2024-0002 | OSD-207 |
| Feature engineering from meta-data for prediction of differentially expressed genes: An investigation of Mus musculus exposed to space-conditions | Okwori M and Eslami A, (2024). Feature engineering from meta-data for prediction of differentially expressed genes: An investigation of Mus musculus exposed to space-conditions, Computational Biology and Chemistry. doi.org/10.1016/j.compbiolchem.2024.108026 | OSD-47, OSD-98, OSD-100, OSD-101, OSD-102, OSD-103, OSD-104, OSD-105, OSD-168, OSD-242 |
| Gut permeability among Astronauts during Space missions | Akinsuyi O S, Xhumari J, Ojeda A, Roesch L F W, (2024). Gut permeability among Astronauts during Space missions, Life Sciences Space Research. doi.org/10.1016/j.lssr.2024.03.003 | OSD-247, OSD-249, OSD-466, OSD-530, OSD-667 |
| Inspiration4 data access through the NASA Open Science Data Repository | Sanders L M, Grigorev K A, Scott R T, Saravia-Butler A M, Polo S L, Gilbert R, Overbey E G, et al, (2024). Inspiration4 data access through the NASA Open Science Data Repository, npj microgravity. doi.org/10.1038/s41526-024-00393-5 | OSD-569, OSD-569, OSD-570, OSD-570, OSD-571, OSD-571, OSD-572, OSD-572, OSD-573, OSD-573, OSD-574, OSD-574, OSD-575, OSD-575, OSD-630, OSD-630, OSD-656, OSD-656, OSD-687, OSD-687 |
| NASA GeneLab derived microarray studies of Mus musculus and Homo sapiens organisms in altered gravitational conditions | Adamopoulos K I, Sanders L M, Costes S V, (2024). NASA GeneLab derived microarray studies of Mus musculus and Homo sapiens organisms in altered gravitational conditions, npj microgravity. doi.org/10.1038/s41526-024-00392-6 | OSD-4, OSD-5, OSD-13, OSD-18, OSD-21, OSD-25, OSD-29, OSD-30, OSD-32, OSD-33, OSD-48, OSD-50, OSD-51, OSD-52, OSD-54, OSD-55, OSD-56, OSD-61, OSD-63, OSD-107, OSD-111, OSD-114, OSD-116, OSD-118, OSD-124, OSD-125, OSD-128, OSD-129, OSD-135, OSD-172, OSD-174, OSD-188, OSD-189, OSD-195, OSD-198, OSD-227, OSD-232, OSD-283, OSD-297, OSD-324, OSD-370, OSD-396, OSD-484, OSD-536, OSD-545, OSD-546, OSD-547 |
| Substrate Matters: Ionic Silver Alters Lettuce Growth, Nutrient Uptake, and Root Microbiome in a Hydroponics System | Spencer L, Costine B, Irwin T, Dixit A, Spern C, Diaz A, Lozzi B, (2024). Substrate Matters: Ionic Silver Alters Lettuce Growth, Nutrient Uptake, and Root Microbiome in a Hydroponics System, microorganisms. doi.org/10.3390/microorganisms12030515 | |
| Using single-sample networks to identify the contrasting patterns of gene interactions and reveal the radiation dose-dependent effects in multiple tissues of spaceflight mice | Zhang Y, Zhao L, Sun Y, (2024). Using single-sample networks to identify the contrasting patterns of gene interactions and reveal the radiation dose-dependent effects in multiple tissues of spaceflight mice, npj microgravity. doi.org/10.1038/s41526-024-00383-7 | OSD-47, OSD-98, OSD-99, OSD-100, OSD-101, OSD-102, OSD-103, OSD-104, OSD-105, OSD-137, OSD-162, OSD-163, OSD-164, OSD-168, OSD-173, OSD-194, OSD-238, OSD-240, OSD-241, OSD-242, OSD-243, OSD-244, OSD-245, OSD-246, OSD-247, OSD-248, OSD-253, OSD-288, OSD-379, OSD-401, OSD-546 |
| Construction of dose prediction model and identification of sensitive genes for space radiation based on single-sample networks under spaceflight conditions | Zhang Y, Du X, Zhao L, Sun Y, (2024). Construction of dose prediction model and identification of sensitive genes for space radiation based on single-sample networks under spaceflight conditions, International Journal of Radiation Biology. doi.org/10.1080/09553002.2024.2327393 | |
| Countermeasures for cardiac fibrosis in space travel: It takes more than a towel for a hitchhiker’s guide to the galaxy | Paar V, Jiang S, Enriquez A, Kim J, Brunetta H S, Muratani M, Kubik A, et al (2023). Countermeasures for cardiac fibrosis in space travel: It takes more than a towel for a hitchhiker’s guide to the galaxy, ResearchSquare. https://doi.org/10.21203/rs.3.rs-2351744/v1 | OSD-530 |
| Key Genes, Altered Pathways and Potential Treatments for Muscle Loss in Astronauts and Sarcopenic Patients | Caicedo A, Castaneda V, Diaz J, Haro-Vinueza A, Park J, Kim J, Overbey E, et al, (2023). Key Genes, Altered Pathways and Potential Treatments for Muscle Loss in Astronauts and Sarcopenic Patients, ResearchSquare. https://doi.org/10.21203/rs.3.rs-2819258/v1 | OSD-52 |
| Intergalactic Interactions – Network Biology in Rodents from Spaceflight and Terra Firma | Hacking S M, Sargin Z E, (2023). Intergalactic Interactions – Network Biology in Rodents from Spaceflight and Terra Firma, ResearchSquare. https://doi.org/10.21203/rs.3.rs-3711156/v1 | OSD-247, OSD-238, OSD-240, OSD-243, OSD-248 |
| Batch effect correction methods for NASA GeneLab transcriptomic datasets | Sanders L M, Chok H, Samson F, Acuna A U, Polo S H L, Boyko V, Chen Y C, et al (2023). Batch effect correction methods for NASA GeneLab transcriptomic datasets, Frontiers in Astronomy and Space Sciences. doi: 10.3389/fspas.2023.1200132 | OSD-47, OSD-48, OSD-137, OSD-168, OSD-173, OSD-242, OSD-245 |
| Designing a Novel Monitoring Approach for the Effects of Space Travel on Astronauts’ Health | Sakharkar A and Yang J, (2023). Designing a novel monitoring approach for the effects of space travel on astronauts’ health, Life. doi.org/10.3390/life13020576 | OSD-174 |
| Efficacy of the random positioning machine as a terrestrial analogue to microgravity in studies of seedling phototropism | Hughes A M, Vandenbrink J P, and Kiss J Z, (2023). Efficacy of the random positioning machine as a terrestrial analogue to microgravity in studies of seedling phototropism, Microgravity Science and Technology. doi: 10.1007/s12217-023-10066-9 | OSD-251 |
| Explainable machine learning identifies multi-omics signatures of muscle response to spaceflight in mice | Li K, Desai R, Scott R T, Steele J R, Machado M, Demharter S, Hoarfrost A, et al (2023). Explainable machine learning identifies multi-omics signatures of muscle response to spaceflight in mice, npj Microgravity. doi: 10.1038/s41526-023-00337-5 | OSD-104, OSD-104, OSD-105, OSD-105, OSD-488, OSD-488 |
| Functional Meta-Analysis of the Proteomic Responses of Arabidopsis Seedlings to the Spaceflight Environment Reveals Multi-Dimensional Sources of Variability across Spaceflight Experiments | Olanrewaju G O, Kruse C P S, and Wyatt S E, (2023). Functional Meta-Analysis of the Proteomic Responses of Arabidopsis Seedlings to the Spaceflight Environment Reveals Multi-Dimensional Sources of Variability across Spaceflight Experiment, International Journal of Molecular Sciences. doi.org/10.3390/ijms241914425 | OSD-38, OSD-522 |
| Investigating the effects of chronic low-dose radiation exposure in the liver of a hypothermic zebrafish model | Cahill T, da Silveira W A, Renaud L, Wang H, Williamson T, Chung D, Chan S, et al, (2023). Investigating the effects of chronic low-dose radiation exposure in the liver of a hypothermic zebrafish model, Scientific Reports. doi.org/10.1038/s41598-022-26976-4 | OSD-47 |
| Large Maf transcription factor family is a major regulator of fast type IIb myofiber determination | Sadaki S, Fujita R, Hayashi T, Nakamura A, Okamura Y, Fuseya S, Hamada M, et al, (2023). Large Maf transcription factor family is a major regulator of fast type IIb myofiber determination, Cell Reports. doi.org/10.1016/j.celrep.2023.112289 | OSD-104 |
| Arabidopsis telomerase takes off by uncoupling enzyme activity from telomere length maintenance in space | Barcenilla B B, Meyers A D, Castillo-Gonzalez C, Young P, Min J H, Song J, Phadke C, et al (2023). Arabidopsis telomerase takes off by uncoupling enzyme activity from telomere length maintenance in space, Nature Communications. doi.org/10.1038/s41467-023-41510-4 | OSD-38, OSD-120, OSD-218, OSD-427 |
| Meta-analysis of the space flight and microgravity response of the Arabidopsis plant transcriptome | Barker R, Kruse C P S, Johnson C, Saravia-Butler A, Fogle H, Chang H S, Trane R M, et al (2023). Meta-analysis of the space flight and microgravity response of the Arabidopsis plant transcriptome, npj Microgravity. doi.org/10.1038/s41526-023-00247-6 | OSD-7, OSD-17, OSD-37, OSD-38, OSD-44, OSD-46, OSD-120, OSD-121, OSD-136, OSD-147, OSD-205, OSD-208, OSD-213, OSD-218, OSD-251 |
| Skeletal muscle gene expression dysregulation in long-term spaceflights and aging is clock-dependent | Malhan D, Yalçin M, Schoenrock B, Blottner D, and Relógio A, (2023). Skeletal muscle gene expression dysregulation in long-term spaceflights and aging is clock-dependent, npj Microgravity. doi.org/10.1038/s41526-023-00273-4 | OSD-99, OSD-101, OSD-103, OSD-104, OSD-105, OSD-370 |
| Transcriptomic Signature of the Simulated Microgravity Response in Caenorhabditis elegans and Comparison to Spaceflight Experiments | Çelen I, Jayasinghe A, Doh J H, and Sabanayagam C R, (2023). Transcriptomic Signature of the Simulated Microgravity Response in Caenorhabditis elegans and Comparison to Spaceflight Experiments, Cells. doi.org/10.3390/cells12020270 | OSD-41, OSD-42, OSD-112, OSD-113 |
| Assessing the Nucleotide-Level Impact of Spaceflight Stress using RNA-Sequencing Data | Knight M S, Doherty C J, Nielsen D M, (2022). Assessing the Nucleotide-Level Impact of Spaceflight Stress using RNA-Sequencing Data, bioRxiv. https://doi.org/10.1101/2022.12.01.518235 | OSD-223 |
| Validating Causal Diagrams of Human Health Risks for Spaceflight: An Example Using Bone Data from Rodents | Reynolds R J, Scott R T, Turner R T, Iwaniec U T, Bouxsein M L, Sanders L M, Antonsen E L, (2022). Validating Causal Diagrams of Human Health Risks for Spaceflight: An Example Using Bone Data from Rodents, Biomedicines. https://doi.org/10.3390/biomedicines10092187 | OSD-310, OSD-351, OSD-477, OSD-489 |
| A multi omics longitudinal study of the murine retinal response to chronic low dose irradiation and simulated microgravity | Kothiyal P, Eley G, Ilangovan H, Hoadley K A, Elgart S R, Mao X W, and Eslami P (2022). A multi omics longitudinal study of the murine retinal response to chronic low dose irradiation and simulated microgravity, Scientific Reports. doi.org/10.1038/s41598-022-19360-9 | OSD-203 |
| Challenges and considerations for single-cell and spatially resolved transcriptomics sample collection during spaceflight | Overbey E G, Das S, Cope H, Madrigal P, Andrusivova Z, Frapard S, Klotz R, et al, (2022). Challenges and considerations for single-cell and spatially resolved transcriptomics sample collection during spaceflight, Cell Reports Methods. doi.org/10.1016/j.crmeth.2022.100325 | OSD-402, OSD-403, OSD-404, OSD-405 |
| Detection of Target Genes for Drug Repurposing to Treat Skeletal Muscle Atrophy in Mice Flown in Spaceflight | Manian V, Orozco-Sandoval J, Diaz-Martinez V, Janwa H, and Agrinsoni C, (2022). Detection of Target Genes for Drug Repurposing to Treat Skeletal Muscle Atrophy in Mice Flown in Spaceflight, Genes. doi.org/10.3390/genes13030473 | OSD-21, OSD-99, OSD-101, OSD-103, OSD-104, OSD-111, OSD-135 |
| DNA methylation dynamics associated with long-term isolation of simulated space travel | Hou F, Zhou X, Zhou S, Liu H, Huang Y E, Yuan M, Zhu J, et al (2022). DNA methylation dynamics associated with long-term isolation of simulated space travel, iScience. doi: 10.1016/j.isci.2022.104493. | OSD-140 |
| Extraterrestrial Gynecology: Could Spaceflight Increase the Risk of Developing Cancer in Female Astronauts? An Updated Review | Drago-Ferrante R, Di Fiore R, Karouia F, Subbannayya Y, Das S, Mathyk B A, Arif S, et al (2022). Extraterrestrial Gynecology: Could Spaceflight Increase the Risk of Developing Cancer in Female Astronauts? An Updated Review, Int. J. Mol. Sci. doi: https://doi.org/ 10.3390/ijms23137465 | |
| In Vitro Relationships of Galactic Cosmic Radiation and Epigenetic Clocks in Human Bronchial Epithelial Cells | Nwanaji-Enwerem J C, Boileau P, Galazka J M, (2022). In Vitro Relationships of Galactic Cosmic Radiation and Epigenetic Clocks in Human Bronchial Epithelial Cells, Environmental and Molecular Mutagenesis. doi.org/10.1002/em.22483 | OSD-317 |
| Machine learning algorithm to characterize antimicrobial resistance associated with the International Space Station surface microbiome | Madrigal P, Singh N K, Wood J M, Gaudioso E, Hernández del Olmo F, Mason C E, Venkateswaran K, and Beheshti A, (2022). Machine learning algorithm to characterize antimicrobial resistance associated with the International Space Station surface microbiome, Microbiome. doi.org/10.1186/s40168-022-01332-w | OSD-67, OSD-69, OSD-302, OSD-303, OSD-309, OSD-311, OSD-350 |
| Multidrug-resistant Acinetobacter pittii is adapting to and exhibiting potential succession aboard the International Space Station. | Tierney B T, Singh N K, Simpson A C, Hujer A M, Bonomo R A, Mason C E, and Venkateswaran K, (2022). Multidrug-resistant Acinetobacter pittii is adapting to and exhibiting potential succession aboard the International Space Station, Microbiome. doi.org/10.1186/s40168-022-01358-0 | OSD-252 |
| Muscle atrophy phenotype gene expression during spaceflight is linked to a metabolic crosstalk in both the liver and the muscle in mice | Vitry G, Finch R, Mcstay G, Behesti A, De jean S, Larose T, Wotring V, et al (2022). Muscle atrophy phenotype gene expression during spaceflight is linked to a metabolic crosstalk in both the liver and the muscle in mice, iScience. doi.org/10.1016/j.isci.2022.105213 | OSD-103, OSD-168 |
| Omics studies of plant biology in spaceflight: A critical review of recent experiments | Hughes A M and Kiss J Z (2022). Omics studies of plant biology in spaceflight: A critical review of recent experiments, Frontiers in Astronomy and Space Sciences. doi.org/10.3389/fspas.2022.964657 | OSD-7, OSD-120 |
| Plant Space Biology in the Genomics Age | Meyers A and Wyatt S E, (2022). Plant Space Biology in the Genomics Age, Annual Plant Reviews. doi:10.1002/9781119312994.apr0784 | OSD-7, OSD-8, OSD-16, OSD-17, OSD-22, OSD-37, OSD-38, OSD-44, OSD-45, OSD-46, OSD-57, OSD-59, OSD-120, OSD-121, OSD-134, OSD-136, OSD-144, OSD-147, OSD-193, OSD-205, OSD-208, OSD-210, OSD-213, OSD-217, OSD-218, OSD-219, OSD-220, OSD-223, OSD-251, OSD-267, OSD-268, OSD-269, OSD-281, OSD-282, OSD-284, OSD-296, OSD-301, OSD-307, OSD-313, OSD-314, OSD-320, OSD-321, OSD-329, OSD-346, OSD-375 |
| Recent transcriptomic studies to elucidate the plant adaptive response to spaceflight and to simulated space environments | Manzano A, Carnero-Diaz E, Herranz R, and Medina F J, (2022). Recent transcriptomic studies to elucidate the plant adaptive response to spaceflight and to simulated space environments, iScience. doi.org/10.1016/j.isci.2022.104687 | OSD-7, OSD-8, OSD-17, OSD-37, OSD-38, OSD-44, OSD-120, OSD-121, OSD-144, OSD-147, OSD-205, OSD-213, OSD-217, OSD-218, OSD-220, OSD-223, OSD-251, OSD-284, OSD-313, OSD-314, OSD-321, OSD-416, OSD-427 |
| Reducing virus infection risk in space environments through nutrient supplementation | Li H, Xue Y W, Quan Y, and Zhang H Y, (2022). Reducing virus infection risk in space environments through nutrient supplementation, Genes. doi.org/10.3390/genes13091536 | OSD-140 |
| Space omics research in Europe: contributions, geographical distribution and ESA member state funding schemes | Deane C S, Borg J, Cahill T, Carnero-Diaz E, Etheridge T, Hardiman G, Leys N, (2022). Space omics research in Europe: contributions, geographical distribution and ESA member state funding schemes, iScience. https://doi.org/10.1016/j.isci.2022.103920 | |
| An integrative network science and artificial intelligence drug repurposing approach for muscle atrophy in spaceflight microgravity. | Manian V, Orozco-Sandoval J, and Diaz-Martinez V, (2021). An integrative network science and artificial intelligence drug repurposing approach for muscle atrophy in spaceflight microgravity, Frontiers in Cell and Developmental Biology. doi: 10.3389/fcell.2021.732370 | OSD-4, OSD-244, OSD-245, OSD-246, OSD-288, OSD-289 |
| Detection of Genes in Arabidopsis thaliana L. Responding to DNA Damage from Radiation and Other Stressors in Spaceflight | Manian V, Orozco-Sandoval J, and Diaz-Martinez V, (2021). Detection of Genes in Arabidopsis thaliana L. Responding to DNA Damage from Radiation and Other Stressors in Spaceflight, Genes. doi.org/10.3390/genes12060938 | OSD-7, OSD-37, OSD-38, OSD-46, OSD-120 |
| Immunological and hematological outcomes following protracted low dose/low dose rate ionizing radiation and simulated microgravity | Paul A M, Overbey E G, da Silveira W A, Szewczyk N, Nishiyama N C, Pecaut M J, Anand S, et al, (2021). Immunological and hematological outcomes following protracted low dose/low dose rate ionizing radiation and simulated microgravity, Scientific Reports. doi.org/10.1038/s41598-021-9043 | |
| Knowledge Network Embedding of Transcriptomic Data from Spaceflown Mice Uncovers Signs and Symptoms Associated with Terrestrial Diseases | Nelson, C.A., Acuna, A.U., Paul, A.M., Scott, R.T., Butte, A.J., Cekanaviciute, E, Baranzini, S.E., and Costes, S.V., (2021). Knowledge Network Embedding of Transcriptomic Data from Spaceflown Mice Uncovers Signs and Symptoms Associated with Terrestrial Diseases, Life. doi.org/10.3390/life11010042 | OSD-4, OSD-244, OSD-245, OSD-246, OSD-288, OSD-289 |
| Mammalian and Invertebrate Models as Complementary Tools for Gaining Mechanistic Insight on Muscle Responses to Spaceflight | Cahill T, Cope H, Bass J J, Overbey E G, Gilbert R, da Silveira W A, Paul A M, et al (2021). Mammalian and Invertebrate Models as Complementary Tools for Gaining Mechanistic Insight on Muscle Responses to Spaceflight, International Journal of Molecular Sciences. doi.org/10.3390/ijms22179470 | OSD-3, OSD-21, OSD-99, OSD-103, OSD-104, OSD-113, OSD-370 |
| NASA GeneLab RNA-seq consensus pipeline: standardized processing of short-read RNA-seq data | Overbey E G, Saravia-Butler A M, Zhang Z, Rathi K S, Fogle H, da Silveira W A, Barker R J, et al, (2021). NASA GeneLab RNA-seq consensus pipeline: standardized processing of short-read RNA-seq data, iScience. doi.org/10.1016/j.isci.2021.102361 | OSD-168, OSD-245 |
| Network Analysis of Gene Transcriptions of Arabidopsis thaliana in Spaceflight Microgravity | Manian, V., Orozco, J., Gangapuram, H., Janwa, H., and Agrinsoni, C., (2021). Network Analysis of Gene Transcriptions of Arabidopsis thaliana in Spaceflight Microgravity, Genes. doi.org/10.3390/genes12030337 | OSD-7, OSD-120 |
| Rad-Bio-App: a discovery environment for biologists to explore spaceflight-related radiation exposures | Barker R, Costes SV, Miller J, Gebre SG, Lombardino J, Gilroy S, (2021). Rad-Bio-App: a discovery environment for biologists to explore spaceflight-related radiation exposures, NPJ Microgravity. doi.org/10.1038/s41526-021-00143-x | OSD-4, OSD-7, OSD-16, OSD-17, OSD-25, OSD-33, OSD-41, OSD-44, OSD-50, OSD-54, OSD-58, OSD-59, OSD-61, OSD-62, OSD-72, OSD-75, OSD-83, OSD-87, OSD-95, OSD-96, OSD-108, OSD-112, OSD-116, OSD-120, OSD-121, OSD-133, OSD-147, OSD-205, OSD-207, OSD-213, OSD-223, OSD-243, OSD-244, OSD-245, OSD-246, OSD-247, OSD-248, OSD-249 |
| Reanalysis of the Mars500 experiment reveals common gut microbiome alterations in astronauts induced by long-duration confinement | Brereton N J B, Pitre F E, Gonzalez E., (2021). Reanalysis of the Mars500 experiment reveals common gut microbiome alterations in astronauts induced by long-duration confinement, Computational and Structural Biotechnology Journal. doi.org/10.1016/j.csbj.2021.03.040 | OSD-191 |
| A Longitudinal Epigenetic Aging and Leukocyte Analysis of Simulated Space Travel: The Mars-500 Mission | Nwanaji-Enwerem, J. C., Nwanaji-Enwerem, U., Van Der Laan, L., Galazka, J. M., Redeker, N. S., and Cardenas, A., (2020). A Longitudinal Epigenetic Aging and Leukocyte Analysis of Simulated Space Travel: The Mars-500 Mission, Cell Reports. doi.org/0.1016/j.celrep.2020.108406 | OSD-140 |
| A New Era for Space Life Science: International Standards for Space Omics Processing | Rutter, L., Barker, R., Bezdan, D., Cope, H., Costes, S. V., Degoricija, L., Fisch, K. M., et al., (2020). A New Era for Space Life Science: International Standards for Space Omics Processing, Patterns. doi.org/10.1016/j.patter.2020.100148 | |
| Advancing the Integration of Biosciences Data Sharing to Further Enable Space Exploration | Scott, R.T., Grigorev, K., Mackintosh, G., Gebre, S. G., Mason, C. E., Del Alto, M. E., and Costes, S. V., (2020). Advancing the Integration of Biosciences Data Sharing to Further Enable Space Exploration, Cell Reports. doi.org/10.1016/j.celrep.2020.108441 | |
| Comparative Transcriptomics Identifies Neuronal and Metabolic Adaptations to Hypergravity and Microgravity in Caenorhabditis elegans | Willis, C. R. G., Szewczyk, N. J., Costes, S. V., Udranszky, I. A., Reinsch, S. S., Etheridge, T., and Conley, C. A., (2020). Comparative Transcriptomics Identifies Neuronal and Metabolic Adaptations to Hypergravity and Microgravity in Caenorhabditis elegans, iScience. doi.org/10.1016/j.isci.2020.101734 | OSD-41, OSD-112, OSD-113, OSD-190 |
| Comparisons of Transcriptome Profiles from Bacillus subtilis Cells Grown in Space versus High Aspect Ratio Vessel (HARV) Clinostats Reveal a Low Degree of Concordance | Morrison, Michael D., Nicholson, Wayne L. “Comparisons of Transcriptome Profiles from Bacillus subtilis Cells Grown in Space versus High Aspect Ratio Vessel (HARV) Clinostats Reveal a Low Degree of Concordance. Astrobiology 2020, doi.org/10.1089/ast.2020.2235 | OSD-31, OSD-39, OSD-14, OSD-15 |
| Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact | da Silveira, W. A., Fazelinia, H., Rosenthal, S. B., Laiakis, E. C., Kim, M. S., Meydan, C., Kidane, Y., et al., (2020). Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact, Cell. doi.org/10.1016/j.cell.2020.11.002 | OSD-98, OSD-99, OSD-100, OSD-101, OSD-102, OSD-103, OSD-104, OSD-105, OSD-161, OSD-162, OSD-163, OSD-168, OSD-13, OSD-52, OSD-54, OSD-114, OSD-118, OSD-174, OSD-47, OSD-48, OSD-343 |
| Fundamental Biological Features of Spaceflight: Advancing the Field to Enable Deep-Space Exploration | Afshinnekoo, E., Scott, R. T., MacKay, M. J., Pariset, E., Cekanaviciute, E., Barker, R., Gilroy, S., et al., (2020). Fundamental Biological Features of Spaceflight: Advancing the Field to Enable Deep-Space Exploration, Cell. doi.org/10.1016/j.cell.2020.10.050 | |
| Integrated RNA-seq Analysis Indicates Asynchrony in Clock Genes between Tissues under Spaceflight | Fujita, S-I, Rutter, L., Ong, Q., Muratani, M. (2020). Integrated RNA-seq Analysis Indicates Asynchrony in Clock Genes between Tissues under Spaceflight. Life 2020, 10(9), 196; doi.org/10.3390/life10090196 | OSD-98,, OSD-99, OSD-101, OSD-102, OSD-103, OSD-104, OSD-105, OSD-168, OSD-48 |
| MicroRNAs (miRNAs), the final frontier: The hidden master regulators impacting biological responses in all organisms due to spaceflight | Vandenburg, C., Beheshti, A. (2020). MicroRNAs (miRNAs), the final frontier: The hidden master regulators impacting biological responses in all organisms due to spaceflight. The Health Risks of Extraterrestrial Environments, March 9, 2020. | |
| NASA GeneLab Platform Utilized for Biological Response to Space Radiation in Animal Models | McDonald, T. J., Stainforth, R., Miller, J., Cahill, T., da Silveira, W. A., Rathi, K. S., Hardiman, G., Taylor, D., Costes, S. V., Chauhan, V., Meller, R., Beheshti, A. (2020). NASA GeneLab Platform Utilized for Biological Response to Space Radiation in Animal Models. Cancers 2020, 12(2), 381; doi.org/10.3390/cancers12020381 (registering DOI). | OSD-63, OSD-52, OSD-114, OSD-21, OSD-4, OSD-47, OSD-25, OSD-98, OSD-99, OSD-100, OSD-101, OSD-102, OSD-103, OSD-104, OSD-105, OSD-168, OSD-242,, OSD-161, OSD-162, OSD-163, OSD-168, OSD-61, OSD-111, OSD-80, OSD-109, OSD-73, OSD-117 |
| NASA GeneLab: interfaces for the exploration of space omics data | Berrios D C, Galazka J, Grigorev K, Gebre S, and Costes S V, (2020). NASA GeneLab: interfaces for the exploration of space omics data, Nucleic Acids Research. doi: 10.1093/nar/gkaa887 | |
| Revamping Space-omics in Europe | Madrigal, P., Gabel, A., Villacampa, A., Manzano, A., Deane, C. S., Bezdan, D., Carnero-Diaz, E., et al., (2020). Revamping Space-omics in Europe, Cell Systems. doi.org/10.1016/j.cels.2020.10.006 | |
| RNAseq Analysis of Rodent Spaceflight Experiments Is Confounded by Sample Collection Techniques | Polo, S. L., Saravia-Butler, A. M., Boyko, V., Dinh, M. T., Chen, Y., Fogle, H., Reinsch, S. S., et al., (2020). RNAseq Analysis of Rodent Spaceflight Experiments Is Confounded by Sample Collection Techniques, iScience. doi.org/10.1016/j.isci.2020.101733 | OSD-47, OSD-48, OSD-49, OSD-168, OSD-235, OSD-236 |
| Test of Arabidopsis Space Transcriptome: A Discovery Environment to Explore Multiple Plant Biology Spaceflight Experiments | Barker, R., Rasmussen, K., Gilroy, S. (2020). Test of Arabidopsis Space Transcriptome: A Discovery Environment to Explore Multiple Plant Biology Spaceflight Experiments, Frontiers Plant Science, 2020. Mar 4;11:147. doi.org/10.3389/fpls.2020.00147. eCollection 2020. | OSD-7, OSD-8, OSD-16, OSD-17, OSD-22, OSD-37, OSD-38, OSD-44, OSD-47, OSD-120, OSD-121, OSD-14, OSD-144, OSD-147, OSD-205, OSD-208, OSD-213, OSD-217, OSD-251 |
| Validation of a New Rodent Experimental System to Investigate Consequences of Long Duration Space Habitation | Choi, S.Y., Saravia-Butler, A., Shirazi-Fard, Y., Levenson-Gower, D., Stodieck, L. S., Cadena, S. M., Beege, J., Solis, S., Ronca, A., Globus, R. K. (2020). Validation of a New Rodent Experimental System to Investigate Consequences of Long Duration Space Habitation. Sci Rep 10, 2336 (2020). doi.org/10.1038/s41598-020-58898-4 | OSD-48 |
| Visualizing Omics Data from Spaceflight Samples using the NASA GeneLab Platform | Berrios, D., Weitz, E., Grigorev, K., Costes, S.V., Gebre, S. G., Beheshti, A. 2020, Visualizing Omics Data from Spaceflight Samples using the NASA GeneLab Platform, EPiC Series in Computing, vol 70, pages 89–98, doi.org/10.29007/rh7n | |
| Comparison of Bacillus subtilis transcriptome profiles from two separate missions to the International Space Station | Morrison, D., Fajardo-Cavozos, P., Nicholson, W. L., (2019). Comparison of Bacillus subtilis transcriptome profiles from two separate missions to the International Space Station. npj Microgravity 5, Article number: 1, doi.org/10.1038/s41526-018-0061-0 | OSD-208, OSD-210 |
| Exploring the Effects of Spaceflight on Mouse Physiology using the Open Access NASA GeneLab Data Platform | Beheshti, A., Shirazi-Fard, Y., Choi, S., Berrios, D., Gebre, S. G., Galazaka, J. M., Costes, S.V., (2019). Exploring the Effects of Spaceflight on Mouse Physiology using the Open Access NASA GeneLab Data Platform. J. Vis. Exp.(143) e58447, doi: 10.3791/58447 | |
| GeneLab Database Analyses Suggest Long-Term Impact of Space Radiation on the Cardiovascular System by the Activation of FYN Through Reactive Oxygen Species | Beheshti, A., McDonald, J. T., Miller, J., Grabham, P., Costes, S. C., (2019). GeneLab Database Analyses Suggest Long-Term Impact of Space Radiation on the Cardiovascular System by the Activation of FYN Through Reactive Oxygen Species.Int. J. Mol. Sci,. 20(3), 661; doi.org/10.3390/ijms20030661 | OSD-52, OSD-109, OSD-117 |
| GeneLab: Omics database for spaceflight experiments | Ray, S., Gebre, S., Fogle, H., Berrios, D. C., Tran, P. B., Galazka, J. G., Costes, S. V., (2019). GeneLab: Omics database for spaceflight experiments. Bioinformatics, 35(10), 1753–1759, doi:10.1093/bioinformatics/bty884 | |
| Mice Exposed to Combined Chronic Low-Dose Irradiation and Modeled Microgravity Develop Long-Term Neurological Sequelae | Overbey, E. G., Paul, A. M., da Silveira, W. A., Tahamic, C. G. T., Reinsch, S. S., Szewczyk, N., Stanbouly, S., Wang, C., Galazka, J. M., Mao, X. W. (2019). Mice Exposed to Combined Chronic Low-Dose Irradiation and Modeled Microgravity Develop Long-Term Neurological Sequelae. Int. J. Mol. Sci., 20(17), 4094; doi.org:10.3390/ijms20174094 | OSD-202 |
| Multi-omics analysis of multiple missions to space reveal a theme of lipid dysregulation in mouse liver | Beheshti, A., Chakravarty, K., Fogle, H., Fazelinia, H., da Silveira, W. A., Boyko, V., Polo, S. J. L., Saravia-Butler, A., Hardiman, G., Taylor, D., Galazka, J. M., Costes, S. V. (2019) Multi-omics analysis of multiple missions to space reveal a theme of lipid dysregulation in mouse liver, Sci Rep 9, 19195 (2019) doi.org/10.1038/s41598-019-55869-2 | OSD-168, OSD-47, OSD-25, OSD-137 |
| Reproducible changes in the gut microbiome suggest a shift in microbial and host metabolism during spaceflight | Jiang, P., Green, S. J., Chlipala, G. E., Turek, F. W., Vitaterna, M. H. (2019). Reproducible changes in the gut microbiome suggest a shift in microbial and host metabolism during spaceflight. Microbiome 2019, 7:113, doi.org/10.1186/s40168-019-0724-4 | OSD-48, OSD-168 |
| A microRNA signature and TGF- 1 response were identified as the key master regulators for spaceflight awareness | Beheshti A., Ray S., Fogle H., Berrios D., Costes S.V. (2018). A microRNA signature and TGF- 1response were identified as the key master regulators for spaceflight awareness. PLoS ONE 13(7): e0199621, doi.org/10.1371/journal.pone.0199621 | OSD-25, OSD-21, OSD-63, OSD-111, OSD-4, OSD-61, OSD-48 |
| FAIRness and Usability for Open-access Omics Data Systems | Berrios, D.C., Beheshti, A., Costes, S. V., (2018) FAIRness and Usability for Open-access Omics Data Systems, AMIA Annu Symp Proc. Dec 5;2018:232-241. eCollection 2018. | |
| Global transcriptomic analysis suggests carbon dioxide as an environmental stressor in spaceflight: A systems biology GeneLab case study | Beheshti A., Cekanaviciute, E., Smith, D. J., Costes, S. V., (2018). Global transcriptomic analysis suggests carbon dioxide as an environmental stressor in spaceflight: A systems biology GeneLab case study. Scientific Reports 8, Article number: 4191. | OSD-21, OSD-111, OSD-25, OSD-63, OSD-324 |
| Meta-analysis of data from spaceflight transcriptome experiments does not support the idea of a common bacterial “spaceflight response” | Morrison, M., Nicholson, W. L., (2018). Meta-analysis of data from spaceflight transcriptome experiments does not support the idea of a common bacterial “spaceflight response.” Scientific Reports8, Article number: 14403 | OSD-185, OSD-145, OSD-138, OSD-39, OSD-31, OSD-15, OSD-11 |
| NASA GeneLab Project: Bridging Space Radiation Omics with Ground Studies | Beheshti, A., Miller, J., Kidane, Y., Berrios, D., Gebre, S.G., Costes, S.V., (2018) NASA GeneLab Project: Bridging Space Radiation Omics with Ground Studies. rrj: 189(6), 553-559; doi.org/10.1667/RR15062.1 | |
| Validation of methods to assess the immunoglobulin gene repertoire in tissues obtained from mice on the international space station | Rettig, T. A., Ward, C., Pecaut, M. J., Chapes, S. K. (2017). Validation of methods to assess the immunoglobulin gene repertoire in tissues obtained from mice on the international space station. Gravitational and Space Research: publication of the American Society for Gravitational and Space Research, 5(1), 2-23. | OSD-48, OSD-47, OSD-141 |
Original Publications – 122
| Title | Description | Datasets |
|---|---|---|
| Exposure to elevated relative humidity in laboratory chambers alters fungal gene expression in dust from the International Space Station (ISS) | Balasubrahmaniam N, Nastasi N, Hegarty B, Horack J M, Meyer M E, Haines S R, Dannemiller K C (2025). Exposure to elevated relative humidity in laboratory chambers alters fungal gene expression in dust from the International Space Station (ISS), Scientific Reports. https://doi.org/10.1038/s41598-025-09534-6 | OSD-701 |
| Neuroinflammatory signaling and immune cell infiltration differ in brains of rats exposed to space radiation and social isolation | Adkins A M, Luyo Z M, Boden A F, Heerbrandt R S, Britten R A, Wellman L L, Sanford L D. Neuroinflammatory signaling and immune cell infiltration differ in brains of rats exposed to space radiation and social isolation, Life. https://doi.org/10.3390/life15050747 | |
| Rotifers in space: transcriptomic response of the bdelloid rotifer Adineta vaga aboard the International Space Station | Moris V C, Bruneau L, Berthe J, Coos R, Baselet B, Heuskin A C, Caplin N, et al (2025). Rotifers in space: transcriptomic response of the bdelloid rotifer Adineta vaga aboard the International Space Station, BM Biology. https://doi.org/10.1186/s12915-025-02272-1 | OSD-824 |
| Simulated microgravity triggers a membrane adaptation to stress in E. coli REL606 | Lozzi B, Adepoju L, Espinoza J L, Padgen M, Parra M, Ricco A, Castro-Wallace S, et al (2025). Simulated microgravity triggers a membrane adaptation to stress in E. coli REL606, BMC Microbiology. https://doi.org/10.1186/s12866-025-04064-7 | OSD-728 |
| The Effect of Red-rich and Blue-rich Lighting on the Microbiome of a Tomato Crop Grown Under International Space Station Conditions of High Humidity and Elevated CO2 | Spern C J, Hummerick M E, Khodadad C L M, Morales C, Dixit A R, Spencer L E, Mitchell C, et al (2025). The Effect of Red-rich and Blue-rich Lighting on the Microbiome of a Tomato Crop Grown Under International Space Station Conditions of High Humidity and Elevated CO2, NASA Technical Reports Server (NTRS). | OSD-766 |
| Impact of simulated microgravity on the growth and proteomicprofile of Enterobacter cloacae | Ocampo J, White R E, Ferraro M J, Rice K C, (2025). Impact of simulated microgravity on the growth and proteomicprofile of Enterobacter cloacae, Microbiology Spectrum. doi: 10.1128/spectrum.02446-24 | OSD-788 |
| 37-Day microgravity exposure in 16-Week female C57BL/6J mice is associated with bone loss specific to weight-bearing skeletal sites | Cahill R, Blaber E A, Juran C M, Cheng-Campbell M, Alwood, J S, Shirazi-Fard Y, Almeida E A C, (2025). 37-Day microgravity exposure in 16-Week female C57BL/6J mice is associated with bone loss specific to weight-bearing skeletal sites, PLoS One. doi: 10.1371/journal.pone.0317307 | OSD-804 |
| The International Space Station has a unique and extreme microbial and chemical environment driven by use patterns | Salido R A, Zhao H N, McDonald D, Mannochio-Russo H, Zuffa S, Oles R E, Aron A T, et al (2025). The International Space Station has a unique and extreme microbial and chemical environment driven by use patterns, Cell. https://doi.org/10.1016/j.cell.2025.01.039 | OSD-734 |
| Effects of Space Flight on Inflammasome Activation in the Brain of Mice | Roy U, Hadad R, Rodriguez A A, Saju A, Roy D, Gil M, Keane R W, et al (2025). Effects of Space Flight on Inflammasome Activation in the Brain of Mice, Cells. https://doi.org/10.3390/cells14060417 | OSD-738, OSD-751, OSD-752, EDA |
| The longitudinal behavioral effects of acute exposure to galactic cosmic radiation in female C57BL/6J mice: Implications for deep space missions, female crews, and potential antioxidant countermeasures | Yun S, Kiffer F C, Bancroft G L, Guzman C S, Soler I, Haas H A, Shi R, et al (2025). The longitudinal behavioral effects of acute exposure to galactic cosmic radiation in female C57BL/6J mice: Implications for deep space missions, female crews, and potential antioxidant countermeasures, Journal of Neurochemistry. https://doi.org/10.1111/jnc.16225 | |
| Validated space radiation exposure predictions from earth to mars during Artemis-I | Slaba T C, Rahmanian S, George S, Laramore D, Norbury J W, Werneth C M, Zeitlin C, (2025). Validated space radiation exposure predictions from earth to mars during Artemis-I, Microgravity. https://doi.org/10.1038/s41526-025-00459-y | RadLab |
| Galactic cosmic ray environment predictions for the NASA BioSentinel Mission, part 2:Post-mission validation | Rahmanian S, Slaba T C, George S, Braby L A, Bhattacharya S, Straume T, Santa Maria S R, (2025). Galactic cosmic ray environment predictions for the NASA BioSentinel Mission, part 2:Post-mission validation, Life Sciences in Space Research. https://doi.org/10.1016/j.lssr.2024.10.006 | RadLab |
| Microgravity Accelerates Skeletal Muscle Degeneration: Functional and Transcriptomic Insights from a Muscle Lab-on-Chip Model Onboard the ISS. | Parafati M, Thwin Z, Malany L K, Coen P M, Malany S, (2025). Microgravity Accelerates Skeletal Muscle Degeneration: Functional and Transcriptomic Insights from a Muscle Lab-on-Chip Model Onboard the ISS, bioRxiv. https://doi.org/10.1101/2025.01.26.634580 | |
| Non-DNA radiosensitive targets that initiate persistent behavioral deficits in rats exposed to space radiation | Straume T, Mora A M, Brown J B, Bansal I, Rabin B M, Braby L A, Wyrobek A J, (2024). Non-DNA radiosensitive targets that initiate persistent behavioral deficits in rats exposed to space radiation, Life Sciences in Space Research. https://doi.org/10.1016/j.lssr.2024.12.003 | OSD-490, OSD-492, OSD-495, OSD-626 |
| Artificial Gravity Attenuates the Transcriptomic Response to Spaceflight in the Optic Nerve and Retina | Kremsky I, Pergerson R, Justinen S, Stanbouly S, Willey J, Fuller C A, Takahashi S, et al (2024). Artificial Gravity Attenuates the Transcriptomic Response to Spaceflight in the Optic Nerve and Retina, International Journal of Molecular Science. doi: 10.3390/ijms252212041 | OSD-758, OSD-759 |
| Spatially resolved multiomics on the neuronal effects induced by spaceflight in mice | Masarapu Y, Cekanaviciute E, Andrusivova Z, Westholm J O, Bjorklund A, Fallegger R, Badia-i-Mompel P, et al (2024). Spatially resolved multiomics on the neuronal effects induced by spaceflight in mice, nature communications. https://doi.org/10.1038/s41467-024-48916-8 | OSD-352 |
| Light has a principal role in the physiological adaptation of plants to the spaceflight environment | Zhou M, Paul A-L, Ferl R, (2024). Light has a principal role in the physiological adaptation of plants to the spaceflight environment, ResearchSquare. https://doi.org/10.21203/rs.3.rs-4085160/v1 | OSD-678, OSD-120 |
| Spaceflight-induced contractile and mitochondrial dysfunctionin an automated heart-on- a-chip platform | Mair D B, Tsui J H, Higashi T, Koenig P, Dong Z, Chen J F, Meir J U, et al, (2024). Spaceflight-induced contractile and mitochondrial dysfunctionin an automated heart-on- a-chip platform, Proc Natl Acad Sci. doi: 10.1073/pnas.2404644121 | OSD-737 |
| Predicting how varying moisture conditions impact the microbiome of dust collected from the International Space Station | Nastasi N, Bope A, Meyer M E, Horack J M, Dannemiller K C, (2024). Predicting how varying moisture conditions impact the microbiome of dust collected from the International Space Station, Microbiome. https://doi.org/10.1186/s40168-024-01864-3 | OSD-694 |
| Modeling cellular responses to serum and vitamin D in microgravity using a human kidney microphysiological system | Lidberg K A, Jones-Isaac K, Yang J, Bain J, Wang L, MacDonald J W, Bammler T K, et al, (2024). Modeling celluar responses to serum and vitamin D in microgravity using a human kidney microphysiological system, npj microgravity. https://doi.org/10.1038/s41526-024-00415-2 | OSD-516 |
| Cosmic kidney disease: An integrated pan-omic, physiological and morphological study into spaceflight-induced renal dysfunction | Siew K, Nestler K A, Nelson C, D’Ambrosio V, Zhong C, Li Z, Grillo A, et al, (2024). Cosmic kidney disease: An integrated pan-omic, physiological and morphological study into spaceflight-induced renal dysfunction, Nature Communications. doi: 10.1038/s41467-024-49212-1 | OSD-72, OSD-102, OSD-163, OSD-212, OSD-249, OSD-250, OSD-253, OSD-336, OSD-342, OSD-457, OSD-462, OSD-465, OSD-466, OSD-513, OSD-530, OSD-532, OSD-571, OSD-575, OSD-706, OSD-707, OSD-708, OSD-709, OSD-710, OSD-712 |
| Direct RNA sequencing of astronaut blood reveals spaceflight-associated m6A increases and hematopoietic transcriptional responses | Grigorev K, Nelson T M, Overbey E G, Hourebi N, Kim J, Najjar D, Damle N, et al (2024). Direct RNA sequencing of astronaut blood reveals spaceflight-associated m6A increases and hematopoietic transcriptional responses, Nature Communications. doi: 10.1038/s41467-024-48929-3 | OSD-569 |
| Longitudinal multi-omics analysis of host microbiome architecture and immune responses during short-term spaceflight | Tierney B T, Kim J, Overbey E G, Ryon K A, Foox J, Sierra M A, Bhattacharya C, et al (2024). Longitudinal multi-omics analysis of host microbiome architecture and immune responses during short-term spaceflight, Nature Microbiology. doi: 10.1038/s41564-024-01635-8 | OSD-570, OSD-572, OSD-573, OSD-630 |
| Microbial adaptation to spaceflight is correlated with bacteriophage-encoded functions | Irby I and Broddrick J, (2024). Microbial adaptation to spaceflight is correlated with bacteriophage-encoded functions, Nature Communications. doi: 10.1038/s41467-023-42104-w | OSD-582 |
| Molecular and physiologic changes in the SpaceX Inspiration4 civilian crew | Jones C W, Overbey E G, Lacombe J, Ecker A J, Meydan C, Ryon K, Tierney, B, et al (2024). Molecular and physiologic changes in the SpaceX Inspiration4 civilian crew, Nature. doi: 10.1038/s41586-024-07648-x | OSD-569, OSD-570, OSD-571, OSD-572, OSD-573, OSD-574, OSD-575, OSD-630, OSD-656, OSD-687 |
| Release of CD36-associated cell-free mitochondrial DNA and RNA as a hallmark of space environment response | Husna N, Aiba T, Fujita S, Saito Y, Shiba D, Kudo T, Takahashi S, et al (2024). Release of CD36-associated cell-free mitochondrial DNA and RNA as a hallmark of space environment response, Nature Communications. doi: 10.1038/s41467-023-41995-z | OSD-530, OSD-532 |
| Secretome profiling reveals acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight | Houerbi N, Kim J, Overbey E G, Batra R, Schweickart A, Patras L, Lucotti S, et al (2024). Secretome profiling reveals acute changes in oxidative stress, brain homeostasis, and coagulation following short-duration spaceflight, Nature Communications. doi: 10.1038/s41467-024-48841-w | OSD-530, OSD-569, OSD-571 |
| Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight | Kim J, Tierney B T, Overbey E G, Dantas E, Fuentealba M, Park J, Narayanan S A, et al (2024). Single-cell multi-ome and immune profiles of the Inspiration4 crew reveal conserved, cell-type, and sex-specific responses to spaceflight, Nature Communications. doi: 10.1038/s41467-024-49211-2 | OSD-530, OSD-570, OSD-575 |
| Space radiation damage rescued by inhibition of key spaceflight-associated miRNAs | McDonald J T, Kim J, Farmerie L, Johnson M L, Trovao N S, Arif S, Siew K, et al (2024). Space radiation damage rescued by inhibition of key spaceflight-associated miRNAs, Nature Communications. doi: 10.1038/s41467-024-48920-y | OSD-334, OSD-335, OSD-336, OSD-337, OSD-530, OSD-570, OSD-577 |
| Spatial multi-omics of human skin reveals KRAS and inflammatory responses to spaceflight | Park J, Overbey E G, Narayanan S A, Kim J, Tierney B T, Damle N, Najjar D, et al (2024). Spatial multi-omics of human skin reveals KRAS and inflammatory responses to spaceflight, Nature Communications. doi: 10.1038/s41467-024-48625-2 | OSD-570, OSD-574 |
| Spatiotemporal expression and control of haemoglobin in space | Borg J, Loy C, Kim J, Buhagiar A, Chin C, Damle N, De Valminck I, et al (2024). Spatiotemporal expression and control of haemoglobin in space, Nature Communications. doi: 10.1038/s41467-024-49289-8 | OSD-530, OSD-570 |
| Telomeric RNA (TERRA) increases in response to spaceflight and high-altitude climbing | Al-Turki T M, Maranon D G, Nelson C B, Lewis A M, Luxton J J, Taylor L E, Altina N, et al (2024). Telomeric RNA (TERRA) increases in response to spaceflight and high-altitude climbing, Communications Biology. doi: 10.1038/s42003-024-06014-x | OSD-569, OSD-570 |
| The Space Omics and Medical Atlas (SOMA) and international astronaut biobank | Overbey E G, Kim J, Tierney B T, Park J, Houerbi N, Lucaci A G, Medina S G, et al (2024). The Space Omics and Medical Atlas (SOMA) and international astronaut biobank, Nature. doi: 10.1038/s41586-024-07639-y | OSD-569, OSD-570, OSD-571, OSD-572, OSD-573, OSD-574, OSD-575, OSD-630, OSD-656 |
| Drosophila parasitoids go to space: Unexpected effects of spaceflight on hosts and their parasitoids | Chou J, Ramroop J R, Saravia-Butler A M, Wey B, Lera M P, Torres M L, Heavner M E, et al (2024). Drosophila parasitoids go to space: Unexpected effects of spaceflight on hosts and their parasitoids, iScience. doi.org/10.1016/j.isci.2023.108759 | OSD-588, OSD-609, OSD-610 |
| Genome and clonal hematopoiesis stability contrasts with immune, cfDNA, mitochondrial, and telomere length changes during short duration spaceflight | Garcia-Medina J S, Sienkiewicz K, Narayanan S A, Overbey E G, Grigorev K, Ryon K A, Burke M, et al (2024). Genome and clonal hematopoiesis stability contrasts with immune, cfDNA, mitochondrial, and telomere length changes during short duration spaceflight, Precision Clinical Medicine. DOI: 10.1093/pcmedi/pbae007 | OSD-570, OSD-572, OSD-573, OSD-630 |
| Sexual dimorphism during integrative endocrine and immune responses to ionizing radiation in mice | Burke M, Wong K, Talyansky Y, Mhatre S D, Mitchell C, Juran C M, Olson, et al (2024). Sexual dimorphism during integrative endocrine and immune responses to ionizing radiation in mice, Scientific Reports. doi: 10.1038/s41598-023-33629-7 | OSD-566 |
| Single-molecule long-read methylation profiling reveals regional DNA methylation regulated by Elongator Complex Subunit 2 in Arabidopsis roots experiencing spaceflight | Zhou M, Riva A, Gauthier M P L, Kladde M P, Ferl R J, Paul A L, (2024). Single-molecule long-read methylation profiling reveals regional DNA methylation regulated by Elongator Complex Subunit 2 in Arabidopsis roots experiencing spaceflight, Biology Direct. doi.org/10.1186/s13062-024-00476-z | OSD-625 |
| Spaceflight effects on human vascular smooth muscle cell phenotype and function | Scotti M M, Wilson B K, Bubenik J L, Yu F, Swanson M S, Allen J B, (2024). Spaceflight effects on human vascular smooth muscle cell phenotype and function, npj microgravity. doi.org/10.1038/s41526-024-00380-w | OSD-635 |
| Biofilm formation of Pseudomonas aeruginosa in spaceflight is minimized on lubricant impregnated surfaces | Flores P, McBride S A, Galazka J M, Varanasi K K, Zea L (2023). Biofilm formation of Pseudomonas aeruginosa in spaceflight is minimized on lubricant impregnated surfaces, npj Microgravity. doi: 10.1038/s41526-023-00316-w | OSD-554, OSD-627 |
| Brachypodium distachyon Seedlings Display Accession-Specific Morphological and Transcriptomic Responses to the Microgravity Environment of the International Space Station | Su S, Levine H, Masson P H, (2023). Brachypodium distachyon seedlings display accession-specific morphological and transcriptomic responses to the microgravity environment of the International Space Station, Life. https://doi.org/10.3390/life13030626 | OSD-375 |
| Glycome profiling and immunohistochemistry uncover changes in cell walls of Arabidopsis thaliana roots during spaceflight | Nakashima J, Pattathil S, Avci U, Chin S, Sparks J A, Hahn M G, Gilroy S, et al (2023). Glycome profiling and immunohistochemistry uncover changes in cell walls of Arabidopsis thaliana roots during spaceflight, npj Microgravity. doi: 10.1038/s41526-023-00312-0 | OSD-615 |
| Simulated galactic cosmic ray exposure activates dose-dependent DNA repair response and down regulates glucosinolate pathways in arabidopsis seedlings | Dixit A R, Meyers A D, Richardson B, Richards J T, Richards S E, Neelam S, Levine H G, et al (2023). Simulated galactic cosmic ray exposure activates dose-dependent DNA repair response and down regulates glucosinolate pathways in arabidopsis seedlings, Frontiers in Plant Science. doi: 10.3389/fpls.2023.1284529 | OSD-658 |
| Specific host metabolite and gut microbiome alterations are associated with bone loss during spaceflight | Bedree J K, Kerns K, Chen T, Lima B P, Liu G, Ha P, Shi J, et al (2023). Specific host metabolite and gut microbiome alterations are associated with bone loss during spaceflight, Cell Reports. doi: 10.1016/j.celrep.2023.112299 | OSD-417 |
| Transcriptomic dynamics in the transition from ground to space are revealed by Virgin Galactic human-tended suborbital spaceflight | Ferl R J, Zhou M, Strickland H F, Haveman N J, Callaham J B, Bandla S, Ambriz D, et al (2023). Transcriptomic dynamics in the transition from ground to space are revealed by Virgin Galactic human-tended suborbital spaceflight, npj Microgravity. doi.org/10.1038/s41526-023-00340-w | OSD-624 |
| Utilizing the KSC Fixation Tube to Conduct Human-Tended Plant Biology Experiments on a Suborbital Spaceflight | Haveman N J, Zhou M, Callaham J, Strickland H F, Houze D, Manning-Roach S, Newsham G, et al, (2023). Utilizing the KSC Fixation Tube to conduct human-tended plant biology experiments on a suborbital spaceflight, Life. doi.org/10.3390/life12111871 | OSD-565 |
| Artificial gravity partially protects space-induced neurological deficits in Drosophila melanogaster | Mhatre S D, Iyer J, Petereit J, Dolling-Boreham R M, Tyryshkina A, Paul A M, Gilbert R, et al (2022). Artificial gravity partially protects space-induced neurological deficits in Drosophila melanogaster, Cell Reports. doi.org/10.1016/j.celrep.2022.111279 | OSD-514 |
| Development of an inexpensive 3D clinostat and comparison with other microgravity simulators using Mycobacterium marinum | Clary J L, France C S, Lind K, Shi R, Alexander J S, Richards J T, Scott R S, et al, (2022). Development of an inexpensive 3D clinostat and comparison with other microgravity simulators using Mycobacterium marinum, Frontiers. doi.org/10.3389/frspt.2022.1032610 | |
| Draft Genome Sequences of Fungi Isolated from Mars 2020 Spacecraft Assembly Facilities | Chander A M, Singh N K, Simpson A C, Seuylemezian A, Mason C E, Venkateswaran K (2022). Draft Genome Sequences of Fungi Isolated from Mars 2020 Spacecraft Assembly Facilities, Microbiology Resource Announcements. doi.org/10.1128/mra.00464-22 | OSD-497, OSD-400 |
| Genomic Characterization of the Titan-like Cell Producing Naganishia tulchinskyi, the First Novel Eukaryote Isolated from the International Space Station | Bijlani S, Parker C, Singh N K, Sierra M A, Foox J, Wang C C C, Mason C E, and Venkateswaran K, (2022). Genomic Characterization of the Titan-like Cell Producing Naganishia tulchinskyi, the First Novel Eukaryote Isolated from the International Space Station, Journal of Fungi. doi.org/10.3390/jof8020165 | OSD-290 |
| Metabolic modeling of the International Space Station microbiome reveals key microbial interactions | Kumar R K, Singh N K, Balakrishnan S, Parker C W, Raman K, Venkateswaran K, (2022). Metabolic modeling of the International Space Station microbiome reveals key microbial interactions, Microbiome. doi.org/10.1186/s40168-022-01279-y | OSD-69 |
| Microbial Tracking-2, a metagenomics analysis of bacteria and fungi onboard the International Space Station | Urbaniak C, Morrison M D, Thissen J B, Karouia F, Smith D J, Mehta S, Jaing C, et al (2022). Microbial Tracking-2, a metagenomics analysis of bacteria and fungi onboard the International Space Station, Microbiome. doi.org/10.1186/s40168-022-01293-0 | OSD-252 |
| Mouse genomic associations with in vitro sensitivity to simulated space radiation | Cekanaviciute E, Tran D, Nguyen H, Macha A L, Pariset E, Langley S, Babbi G, et al, (2022). Mouse genomic associations with in vitro sensitivity to simulated space radiation, Life Sciences in Space Research. doi.org/10.1016/j.lssr.2022.07.006 | OSD-366 |
| Plants grown in Apollo lunar regolith present stress-associated transcriptomes that inform prospects for lunar exploration | Paul A L, Elardo S M, and Ferl R, (2022). Plants grown in Apollo lunar regolith present stress-associated transcriptomes that inform prospects for lunar exploration, Communications Biology. doi.org/10.1038/s42003-022-03334-8 | |
| Quantitative proteomic analytic approaches to identify metabolic changes in the medial prefrontal cortex of rats exposed to space radiation | Laiakis E C, Pinheiro M, Nguyen T, Nguyen H, Beheshti A, Dutta S M, Russell W K, et al (2022). Quantitative proteomic analytic approaches to identify metabolic changes in the medial prefrontal cortex of rats exposed to space radiation, Frontiers in Physiology. doi.org/10.3389/fphys.2022.971282 | OSD-505 |
| Red Light Enhances Plant Adaptation to Spaceflight and Mars g-Levels | Medina F J, Manzano A, Herranz R, and Kiss J Z (2022). Red Light Enhances Plant Adaptation to Spaceflight and Mars g-Levels, Life. doi.org/10.3390/life12101484 | OSD-251, OSD-314, OSD-346 |
| Spaceflight analogue culture enhances the host-pathogen interaction between Salmonella and a 3-D biomimetic intestinal co-culture model | Barrila J, Yang J, Franco Meléndez KP, Yang S, Buss K, Davis TJ, Aronow BJ, et al, (2022). Spaceflight analogue culture enhances the host-pathogen interaction between Salmonella and a 3-D biomimetic intestinal co-culture model, Front Cell Infect Microbiology. doi.org/10.3389/fcimb.2022.705647 | OSD-277 |
| The Maleth program: Malta’s first space mission discoveries on the microbiome of diabetic foot ulcers | Gatt C, Tierney B T, Madrigal P, Mason C E, Beheshti A, Telzerow A, Benes V, et al, (2022). The Maleth program: Malta’s first space mission discoveries on the microbiome of diabetic foot ulcers, Heliyon. doi.org/10.1016/j.heliyon.2022.e12075 | OSD-487 |
| An Analysis of the Effects of Spaceflight and Vaccination on Antibody Repertoire Diversity | Rettig T A, Tan J C, Nishiyama N C, Chapes S K, Pecaut M J, (2021). An Analysis of the Effects of Spaceflight and Vaccination on Antibody Repertoire Diversity, ImmunoHorizons. doi: https://doi.org/10.4049/immunohorizons.2100056 | OSD-141, OSD-164, OSD-201, OSD-214 |
| Cell spinpods are a simple inexpensive suspension culture device to deliver fuid shear stress to renal proximal tubular cells | Hammond T G, Nislow C, Christov I C, Batuman V, Nagrani P P, Barazandeh M, Upadhyay R, et al (2021). Cell spinpods are a simple inexpensive suspension culture device to deliver fuid shear stress to renal proximal tubular cells, Scientific Reports. doi.org/10.1038/s41598-021-00304-8 | |
| Diagnosing an Opportunistic Fungal Pathogen on Spaceflight-Grown Plants Using the MinION Sequencing Platform | Haveman N J, Schuerger A C, (2021). Diagnosing an Opportunistic Fungal Pathogen on Spaceflight-Grown Plants Using the MinION Sequencing Platform, Astrobiology. doi: 10.1089/ast.2021.00491 | |
| Draft Genome Sequences of Aspergillus and Penicillium Species Isolated from the International Space Station and Crew Resupply Vehicle Capsule | Blachowicz, A., Singh, N. K., Wood, J. M., Debieu, M., O’Hara, N. B., Mason, C. E., Venkateswarana, K., (2021). Draft Genome Sequences of Aspergillus and Penicillium Species Isolated from the International Space Station and Crew Resupply Vehicle Capsule, Microbiology Resource Announcements. doi.org/ 10.1128/MRA.01398-20 | OSD-350 |
| Draft genome sequences of heat shock-tolerant microbes isolated from a spacecraft assembly facility. | Wood J M, Peres J B, Bateh J, Singh N K, Aronson H S, Hendrickson R, Mason C E, et al (2021). Draft genome sequences of heat shock-tolerant microbes isolated from a spacecraft assembly facility, Microbiology Resource Announcements. doi.org/10.1128/MRA.00653-21 | |
| Draft Genome Sequences of Various Bacterial Phyla Isolated from the International Space Station | Simpson A C, Urbaniak C, Singh N K, Wood J M, Debieu M, O’Hara N B, Mason C E, (2021). Draft Genome Sequences of Various Bacterial Phyla Isolated from the International Space Station, Microbiology Resource Announcements. DOI: 10.1128/MRA.00214-21 | OSD-361 |
| Effects of Low Dose Space Radiation Exposures on the Splenic Metabolome | Laiakis, E. C., Shuryak, I., Deziel, A., Wang, Y., Barnette, B. L., Yu, Y., Ullrich, R. L., et al., (2021). Effects of Low Dose Space Radiation Exposures on the Splenic Metabolome, International Journal of Molecular Sciences. doi.org/10.3390/ijms22063070 | |
| Evaluating the effect of spaceflight on the host–pathogen interaction between human intestinal epithelial cells and Salmonella Typhimurium | Barrila, J., Sarker, S. F., Hansmeier, N., Yang, S., Buss, K., Briones, N., Park, J., Davis, R. R., Forsyth, R. J., Ott, C. M., Sato, K., Kosnik, C., Yang, A., Shimoda, C., Rayl, N., Ly, D., Landenberger, A., Wilson, S. D., Yamazaki, N., Steel, J., Montano, C., Halden, R.U., Cannon, T., Castro-Wallace, S. L. and Nickerson, C. A., (2021). Evaluating the effect of spaceflight on the host–pathogen interaction between human intestinal epithelial cells and Salmonella Typhimurium, Microgravity. doi.org/10.1038/s41526-021-00136-w | OSD-323 |
| Evaluating the lettuce metatranscriptome with MinION sequencing for future spaceflight food production applications | Haveman N J, Khodadad C L M, Dixit A R, Louyakis A S, Massa G D, Venkateswaran K, and Foster J S, (2021). Evaluating the lettuce metatranscriptome with MinION sequencing for future spaceflight food production applications, npj Microgravity. doi.org/10.1038/s41526-021-00151-x | |
| Long-read sequencing reveals increased occurrence of genomic variants and adenosine methylation in Bacillus pumilus SAFR-032 after long-duration flight exposure onboard the International Space Station | Waters S M, Ledford S M, Wacker A, Verma S, Serda B, McKaig J, Varelas J, et al, (2021). Long-read sequencing reveals increased occurrence of genomic variants and adenosine methylation in Bacillus pumilus SAFR-032 after long-duration flight exposure onboard the International Space Station, International Journal of Astrobiology. doi.org/10.1017/S1473550421000343 | |
| Methylobacterium ajmalii sp. nov., Isolated From the International Space Station | Bijlani, S., Singh, N. K., Eedara, V. V. R., Podile, A. R., Mason, C. E., Wang, C. C. C., and Venkateswaran, K., (2021). Methylobacterium ajmalii sp. nov., Isolated From the International Space Station, Frontiers in Microbiology. doi.org/10.3389/fmicb.2021.639396 | OSD-300 |
| Persistence of Escherichia coli in the microbiomes of red Romaine lettuce (Lactuca sativa cv. ‘Outredgeous’) and mizuna mustard (Brassica rapa var. japonica) – does seed sanitization matter? | Dixit A R, Khodadad C L M, Hummerick M E, Spern C J, Spencer L E, Fischer J A, Curry A B, et al (2021). Persistence of Escherichia coli in the microbiomes of red Romaine lettuce (Lactuca sativa cv. ‘Outredgeous’) and mizuna mustard (Brassica rapa var. japonica) – does seed sanitization matter?, BMC Microbiology. doi.org/10.1186/s12866-021-02345-5 | |
| Spaceflight studies identify a gene encoding an intermediate filament involved in tropism pathways | Shymanovicha T, Vandenbrink J P, Herranz R, Medina F J, Kiss J Z, (2021). Spaceflight studies identify a gene encoding an intermediate filament involved in tropism pathways, Plant Physiology and Biochemistry. doi.org/10.1016/j.plaphy.2021.12.039 | OSD-251 |
| Spatial Characterization of Microbial Communities on Multi-Species Leafy Greens Grown Simultaneously in the Vegetable Production Systems on the International Space Station | Hummerick M E, Khodadad C L M, Dixit A R, Spencer L E, Maldonado-Vasquez G J, Gooden J L, Spern C J, et al (2021). Spatial Characterization of Microbial Communities on Multi-Species Leafy Greens Grown Simultaneously in the Vegetable Production Systems on the International Space Station, Life. doi.org/10.3390/life11101060 | |
| The Impact of Hindlimb Suspension on the Rat Eye: A Molecular and Histological Analysis of the Retina | Theriot C A, Chevez-Barrios P, Loughlin T, Beheshti A, Mercaldo N D, Zanello S B, (2021). The Impact of Hindlimb Suspension on the Rat Eye: A Molecular and Histological Analysis of the Retina, Gravitational and Space Research. doi.org/10.2478/gsr-2021-0007 | |
| Approaches for Surveying Cosmic Radiation Damage in Large Populations of Arabidopsis thaliana Seeds – Antarctic Balloons and Particle Beams | Califar, B., Tucker, R., Cromie, J., Sng, N., Schmitz, R. A., Callaham, J. A., Barbazuk, B., Paul, A-L, Ferl, R. J. (2020). Approaches for Surveying Cosmic Radiation Damage in Large Populations of Arabidopsis thaliana Seeds – Antarctic Balloons and Particle Beams, Gravitational and Space Research 6:2, doi.org/10.2478/gsr-2018-0010 | OSD-210, OSD-210 |
| Beyond Low-Earth Orbit: Characterizing Immune and microRNA Differentials following Simulated Deep Spaceflight Conditions in Mice | Paul, A, M., Cheng-Campbell, M., Blaber, E. A., Anand. S., Bhattacharya, S., Zwart, S. R., Crucian, B. E., et al., (2020). Beyond Low Earth Orbit: Characterizing the Immune Profile Following Simulated Spaceflight Conditions for Deep Space Missions, iScience. doi.org/10.1016/j.isci.2020.101747 | OSD-336 |
| Circulating miRNA Spaceflight Signature Reveals Targets for Countermeasure Development | Malkani, S., Chin, C. R., Cekanaviciute. E., Mortreux, M., Okinula, H., Tarbier, M., Schreurs, A. S., et al., (2020). Circulating miRNA Signature Predicts and Rescues Health Risks Associated with Spaceflight, Cell Reports. doi.org/10.1016/j.celrep.2020.108448 | OSD-334, OSD-335, OSD-336, OSD-337 |
| Competitive Growth Assay of Mutagenized Chlamydomonas reinhardtii Compatible With the International Space Station Veggie Plant Growth Chamber | Zhang, J., Müller, B., Tyre, K. N., Hersh, H. L., Bai, F., Hu, Y., Resende, M., Jr, Rathinasabapathi, B., Settles, A. M. (2020). Competitive Growth Assay of Mutagenized Chlamydomonas reinhardtii Compatible With the International Space Station Veggie Plant Growth Chamber. Frontiers in plant science, 11, 631. doi.org/10.3389/fpls.2020.00631 | OSD-265 |
| Draft Genome Sequences of Enterobacteriales Strains Isolated from the International Space Station | Bharadwaj, A.R., Daudu. R., Singh, N.K., Wood, J.M., Debieu, M., O’Hara, N.B., Karouia, F., Mason, C.E., Venkateswaran, K. (2020) Draft Genome Sequences of Enterobacteriales Strains Isolated from the International Space Station. Microbiology Resource Announcement – 9:e00817-20. doi.org/10.1128/MRA.00817-20. | OSD-302, OSD-311 |
| Draft Genome Sequences of Sphingomonas Species Associated with the International Space Station | Bijlani, S., Singh, N.K., Mason, C.E., Wang, C.C.C., Venkateswaran, K., (2020). Draft genome sequences of Sphingomonas species associated with the International Space Station. Microbiology Resource Announcement, 9:e00578-20. doi.org/10.1128/MRA.00578-20. | OSD-298 |
| Draft Genome Sequences of Tremellomycetes Strains Isolated from the International Space Station | Bijlani, S., Singh, N. K., Mason, C. E., Wang, C. C. C., Venkateswaran, K. (2020). Draft Genome Sequences of Tremellomycetes Strains Isolated from the International Space Station. Microbiology Resource Announcements, 9, 26, e00504-20. | OSD-290 |
| LET-Dependent Low Dose and Synergistic Inhibition of Human Angiogenesis by Charged Particles: Validation of miRNAs that Drive Inhibition | Wuu, Y., Hu, B., Okunola, H., Paul, A. M., Blaber, E. A., Cheng-Campbell, M., Beheshti, A., et al., (2020). LET-Dependent Low Dose and Synergistic Inhibition of Human Angiogenesis by Charged Particles: Validation of miRNAs that Drive Inhibition, iScience. doi.org/10.1016/j.isci.2020.101771 | OSD-334, OSD-336 |
| Microbiological and nutritional analysis of lettuce crops grown on the International Space Station | Khodadad, C. L., Hummerick, M. E., Spencer, L. E., Dixit, A. R., Richards, J. T., Romeyn, M. W., Smith, T. M., Wheeler, R. M., Massa, G. D. (2020) Microbiological and Nutritional Analysis of Lettuce Crops Grown on the International Space Station. Front Plant Sci. 2020 Mar 6;11:199. doi: 10.3389/fpls.2020.00199. | OSD-267, OSD-268, GLDS:269 |
| Prolonged Exposure to Microgravity Reduces Cardiac Contractility and Initiates Remodeling in Drosophila | Walls, S., Diop, S., Birse, R., Elmen, L., Gan, Z., Kalvakuri, S., Pineda, S., et al., (2020). Prolonged Exposure to Microgravity Reduces Cardiac Contractility and Initiates Remodeling in Drosophila, Cell Reports. doi.org/10.1016/j.celrep.2020.108445 | OSD-347 |
| Root skewing-associated genes impact the spaceflight response of Arabidopsis thaliana | Califar, B., Sng, N.J., Zupanska, A., Paul, A-L, Ferl, R.J. (2020). Root skewing-associated genes impact the spaceflight response of Arabidopsis thaliana. Frontiers in Plant Science 2020, 11:239, doi.org/10.3389/fpls.2020.00239 | OSD-218 |
| Sierra Nevada Sweep: Metagenomic Measurements of Bioaerosols Vertically Distributed Across the Troposphere | Jaing, C., Thissen, J., Morrison, M. et al. (2020) Sierra Nevada Sweep: Metagenomic Measurements of Bioaerosols Vertically Distributed Across the Troposphere. Sci Rep 10, 12399. doi.org/10.1038/s41598-020-69188-4 | OSD-256 |
| Spaceflight induces novel regulatory responses in Arabidopsis seedling as revealed by combined proteomic and transcriptomic analyses | Kruse, C, P. S., Meyers, A. D., Basu, P., Hutchinson, S., Luisee, D. R., Wyatt, S. E., (2020). Spaceflight induces novel regulatory responses in Arabidopsis seedling as revealed by combined proteomic and transcriptomic analyses. BCM Plant Biology, 2020; 20:237. doi.org/10.1186/s12870-020-02392-6 | OSD-38 |
| The Importance of Earth Reference Controls in Spaceflight -Omics Research: Characterization of Nucleolin Mutants from the Seedling Growth Experiments | Manzano, A., Villacampa, A., Saez-Vasquez, J., Kiss, J. Z., Medina, F. J., and Herranz, R., (2020). The Importance of Earth Reference Controls in Spaceflight -Omics Research: Characterization of Nucleolin Mutants from the Seedling Growth Experiments, iScience. doi.org/10.1016/j.isci.2020.101686 | OSD-313 |
| The influence of spaceflight on the astronaut salivary microbiome and the search for a microbiome biomarker for viral reactivation | Urbaniak, C., Lorenzi, H., Thissen, J. et al. The influence of spaceflight on the astronaut salivary microbiome and the search for a microbiome biomarker for viral reactivation. Microbiome 8, 56 (2020). doi.org/10.1186/s40168-020-00830-z | OSD-280 |
| Articular cartilage and sternal fibrocartilage respond differently to extended microgravity | Fitzgerald, J., Endicott, J., Hansen, U., & Janowitz, C. (2019). Articular cartilage and sternal fibrocartilage respond differently to extended microgravity. NPJ Microgravity, 5, 3. doi:10.1038/s41526-019-0063-6 | OSD-232 |
| Cell cycle acceleration and changes in essential nuclear functions induced by simulated microgravity in a synchronized Arabidopsis cell culture | Kamal, K. Y., Herranz, R., van Loon, J., & Medina, F. J. (2019). Cell cycle acceleration and changes in essential nuclear functions induced by simulated microgravity in a synchronized Arabidopsis cell culture. Plant Cell Environ, 42(2), 480-494. doi:10.1111/pce. | OSD-144 |
| Differential transcriptional profile through cell cycle progression in Arabidopsis cultures under simulated microgravity | Kamal, K. Y., Herranz, R., van Loon, J., Medina, F. J., Herranz (2019). Differential transcriptional profile through cell cycle progression in Arabidopsis cultures under simulated gravity. ScienceDirect, doi.org/10.1016/j.ygeno.2019.01.007 | OSD-144 |
| Effects of skeletal unloading on the bone marrow antibody repertoire of tetanus toxoid and/or CpG treated C57BL/6J mice | Rettig, T.A., Nishiyama, N.C., Pecaut, M.J., Chapes, S.K., (2019). Effects of skeletal unloading on the bone marrow antibody repertoire of tetanus toxoid and/or CpG treated C57BL/6J mice. Life Sciences in space Research 22:16, doi.org/10.1016/j.lssr.2019.06.001 | OSD-214, OSD-201 |
| Epigenomics in an extraterrestrial environment: organ-specific alteration of DNA methylation and gene expression elicited by spaceflight in Arabidopsis thaliana | Zhou, M., Sng, N. J., LeFrois, C. E., Paul, A-L, Ferl, R. J., (2019). Epigenomics in an extraterrestrial environment: organ-specific alteration of DNA methylation and gene expression elicited by spaceflight in Arabidopsis thaliana. BMC Genomics 20:205, doi:10.1186/s12864-019-5554-z | OSD-217 |
| Establishing Standard Protocols for Bacterial Culture in Biological Research in Canisters (BRIC) Hardware | Morrison, M.D., Fajardo-Cavazos, P., Nicholson, W., (2019). Comparison of Bacillus subtilis transcriptome profiles from two separate missions to the International Space Station. npj Microgravity 5, Article number:1 | OSD-185, OSD-145, OSD-138 |
| HSFA2 Functions in the Physiological Adaptation of Undifferentiated Plant Cells to Spaceflight | Zupanska, A. K., LeFrois, C., Ferl, R. J., Paul, A-L. (2019). HSFA2 Functions in the Physiological Adaptation of Undifferentiated Plant Cells to Spaceflight. Int J Mol Sci, Jan 17;20(2). pii: E390. doi: 10.3390/ijms20020390. | OSD-205 |
| RNA seq analyses of Arabidopsis thaliana seedlings after exposure to blue light phototropic stimuli in microgravity | Herranz, R., Vandenbrink, J.P., Villacampa, A., Manzano, A., Poehlman, W., Feltus, F. A., Kiss, J. Z., Medina, M. J. (2019), RNA seq analyses of Arabidopsis thaliana seedlings after exposure to blue light phototropic stimuli in microgravity, doi.org/10.1002/abj2.1384 | OSD-251 |
| Spaceflight-induced alternative splicing during seedling development in Arabidopsis thaliana | Beisel, N.S., Noble, J., Barbazuk, B. W., Paul, A-L., Ferl, R. J., (2019). Spaceflight-induced alternative splicing during seedling development in Arabidopsis thaliana. npj Microgravity 5:9, doi:10.1038/s41526-019-0070-7 | OSD-218 |
| Variation in the transcriptome of different ecotypes of Arabidopsis thaliana reveals signatures of oxidative stress in plant responses to spaceflight | Choi, W. G., Barker, R. J., Kim, S. H., Swanson, S. J., & Gilroy, S. (2019). Variation in the transcriptome of different ecotypes of Arabidopsis thaliana reveals signatures of oxidative stress in plant responses to spaceflight. Am J Bot, 106(1), 123-136. doi:10.1002/ajb2.1223 | OSD-37 |
| Airborne Bacteria in Earth’s Lower Stratosphere Resemble Taxa Detected in the Troposphere: Results from a New NASA Aircraft Bioaerosol Collector (ABC) | Smith, D. J., Ravichandar, J. D., Jain, S., Griffin, D. W., Yu, H., Tan, Q., . . . McGrath, J. (2018). Airborne Bacteria in Earth’s Lower Stratosphere Resemble Taxa Detected in the Troposphere: Results From a New NASA Aircraft Bioaerosol Collector (ABC). Front Microbiol, 9, 1752. doi:10.3389/fmicb.2018.01752 | OSD-170 |
| Characterization of the naive murine antibody repertoire using unamplified high-throughput sequencing | Rettig, T. A., Ward, C., Bye, B. A., Pecaut, M. J., & Chapes, S. K. (2018). Characterization of the naive murine antibody repertoire using unamplified high-throughput sequencing. PLoS One, 13(1), e0190982. doi:10.1371/journal.pone.0190982 | OSD-141 |
| Comparing RNA Seq and microarray gene expression data in two zones of the Arabidopsis root apex relevant to spaceflight | Krishnamurthy, A., Ferl, R. J., Paul, A-L., (2018). Comparing RNA Seq and microarray gene expression data in two zones of the Arabidopsis root apex relevant to spaceflight. Applications in Plant Sciences, 6(11): e01197, doi:10.1002/aps3.1197 | OSD-208 |
| Detection of antimicrobial resistance genes associated with the International Space Station environmental surfaces | Urbaniak, C., Sielaff, A. C., Frey, K. G., Allen, J. E., Singh, N., Jaing, C., . . . Venkateswaran, K. (2018). Detection of antimicrobial resistance genes associated with the International Space Station environmental surfaces. Sci Rep, 8(1), 814. doi:10.1038/s41598-017-18506-4 | OSD-66 |
| Draft Genome Sequence of a Clinical Isolate of Fusarium fujikuroi Isolated from a Male Patient with Acute Myeloid Leukemia | Urbaniak, C., Dadwal, S., Bagramyan, K., & Venkateswaran, K. (2018). Draft Genome Sequence of a Clinical Isolate of Fusarium fujikuroi Isolated from a Male Patient with Acute Myeloid Leukemia. Genome Announc, 6(25). doi:10.1128/genomeA.00476-18 | |
| Draft Genome Sequences of Two Fusarium oxysporum Isolates Cultured from Infected Zinnia hybrida Plants Grown on the International Space Station | Urbaniak, C., Massa, G., Hummerick, M., Khodadad, C., Schuerger, A., & Venkateswaran, K. (2018). Draft Genome Sequences of Two Fusarium oxysporum Isolates Cultured from Infected Zinnia hybrida Plants Grown on the International Space Station. Genome Announc, 6(20). doi:10.1128/genomeA.00326-18 | OSD-177 |
| Effects of spaceflight on the immunoglobulin repertoire of unimmunized C57BL/6 mice | Ward, C., Rettig, T. A., Hlavacek, S., Bye, B. A., Pecaut, M. J., & Chapes, S. K. (2018). Effects of spaceflight on the immunoglobulin repertoire of unimmunized C57BL/6 mice. Life Sci Space Res (Amst), 16, 63-75. doi:10.1016/j.lssr.2017.11.003 | OSD-164 |
| Multi-drug resistant Enterobacter bugandensis species isolated from the International Space Station and comparative genomic analyses with human pathogenic strains | Singh, N. K., Bezdan, D., Checinska Sielaff, A., Wheeler, K., Mason, C. E., & Venkateswaran, K. (2018). Multi-drug resistant Enterobacter bugandensis species isolated from the International Space Station and comparative genomic analyses with human pathogenic strains. BMC Microbiol, 18(1), 175. doi:10.1186/s12866-018-1325-2 | OSD-67 |
| Succession and persistence of microbial communities and antimicrobial resistance genes associated with International Space Station environmental surfaces | Singh, N. K., Wood, J. M., Karouia, F., & Venkateswaran, K. (2018). Succession and persistence of microbial communities and antimicrobial resistance genes associated with International Space Station environmental surfaces. Microbiome, 6(1), 214. doi:10.1186/s40168-018-0609-y | OSD-69 |
| Comparative transcriptomics indicate changes in cell wall organization and stress response in seedlings during spaceflight | Johnson, C. M., Subramanian, A., Pattathil, S., Correll, M. J., & Kiss, J. Z. (2017). Comparative transcriptomics indicate changes in cell wall organization and stress response in seedlings during spaceflight. Am J Bot, 104(8), 1219-1231. doi:10.3732/ajb.1700079 | OSD-121 |
| Draft Genome Sequences from a Novel Clade of Bacillus cereus Sensu Lato Strains, Isolated from the International Space Station | Venkateswaran, K., Checinska Sielaff, A., Ratnayake, S., Pope, R. K., Blank, T. E., Stepanov, V. G., . . . Bergman, N. H. (2017). Draft Genome Sequences from a Novel Clade of Bacillus cereus Sensu Lato Strains, Isolated from the International Space Station. Genome Announc, 5(32). doi:10.1128/genomeA.00680-17 | OSD-64 |
| Genetic dissection of the Arabidopsis spaceflight transcriptome: Are some responses dispensable for the physiological adaptation of plants to spaceflight? | Paul, A. L., Sng, N. J., Zupanska, A. K., Krishnamurthy, A., Schultz, E. R., & Ferl, R. J. (2017). Genetic dissection of the Arabidopsis spaceflight transcriptome: Are some responses dispensable for the physiological adaptation of plants to spaceflight? PLoS One, 12(6), e0180186. doi:10.1371/journal.pone.0180186 | OSD-120 |
| Growth in spaceflight hardware results in alterations to the transcriptome and proteome | Basu, P., Kruse, C. P. S., Luesse, D. R., & Wyatt, S. E. (2017). Growth in spaceflight hardware results in alterations to the transcriptome and proteome. Life Sci Space Res (Amst), 15, 88-96. doi:10.1016/j.lssr.2017.09.001 | OSD-38 |
| Is spaceflight-induced immune dysfunction linked to systemic changes in metabolism? | Pecaut, M. J., Mao, X. W., Bellinger, D. L., Jonscher, K. R., Stodieck, L. S., Ferguson, V. L., . . . Gridley, D. S. (2017). Is spaceflight-induced immune dysfunction linked to systemic changes in metabolism? PLoS One, 12(5), e0174174. doi:10.1371/journal.pone.0174174 | OSD-108, OSD-125 |
| Nanopore DNA Sequencing and Genome Assembly on the International Space Station | Castro-Wallace, S. L., Chiu, C. Y., John, K. K., Stahl, S. E., Rubins, K. H., McIntyre, A. B. R., . . . Burton, A. S. (2017). Nanopore DNA Sequencing and Genome Assembly on the International Space Station. Sci Rep, 7(1), 18022. doi:10.1038/s41598-017-18364-0 | OSD-84 |
| Non-Toxin-Producing Bacillus cereus Strains Belonging to the B. anthracis Clade Isolated from the International Space Station | Venkateswaran, K., Singh, N. K., Checinska Sielaff, A., Pope, R. K., Bergman, N. H., van Tongeren, S. P., . . . Perry, J. (2017). Non-Toxin-Producing Bacillus cereus Strains Belonging to the B. anthracis Clade Isolated from the International Space Station. mSystems, 2(3). doi:10.1128/mSystems.00021-17 | OSD-64 |
| Transcriptome and proteome responses in RNAlater preserved tissue of Arabidopsis thaliana | Kruse, C. P. S., Basu, P., Luesse, D. R., & Wyatt, S. E. (2017). Transcriptome and proteome responses in RNAlater preserved tissue of Arabidopsis thaliana. PLoS One, 12(4), e0175943. doi:10.1371/journal.pone.0175943 | OSD-38 |
| Whole metagenome profiles of particulates collected from the International Space Station. | Be, N. A., Avila-Herrera, A., Allen, J. E., Singh, N., Sielaff, A. C., Jaing, C., & Venkateswaran, K. (2017). Whole meta genome profiles of particulates collected from the International Space Station. Microbiome, 5:81, doi.org/10.1186/s40168-017-0292-4 | OSD-64 |
| Draft Genome Sequences of Biosafety Level 2 Opportunistic Pathogens Isolated from the Environmental Surfaces of the International Space Station | Checinska Sielaff, A., Singh, N. K., Allen, J. E., Thissen, J., Jaing, C., & Venkateswaran, K. (2016). Draft Genome Sequences of Biosafety Level 2 Opportunistic Pathogens Isolated from the Environmental Surfaces of the International Space Station. Genome Announc, 4(6). doi:10.1128/genomeA.01263-16 | OSD-67 |
| Exposure of Mycobacterium marinum to low-shear modeled microgravity: effect on growth, the transcriptome and survival under stress | Abshire, C., Prasai, K., Soto, I., Shi, R., Concha, M., Baddoo, M., Flemington, E. K., Ennis, D. G., Scott, R. S., Harrison, L. (2016). Exposure of Mycobacterium marinum to low-shear modeled microgravity: effect on growth, the transcriptome and survival under stress. npc Microgravity 2, 16038 (2016). doi.org/10.1038/npjmgrav.2016.38 | OSD-90 |
| Spaceflight Activates Lipotoxic Pathways in Mouse Liver | Jonscher, K. R., Alfonso-Garcia, A., Suhalim, J. L., Orlicky, D. J., Potma, E. O., Ferguson, V. L., . . . Pecaut, M. J. (2016). Correction: Spaceflight Activates Lipotoxic Pathways in Mouse Liver.PLoS One, 11(5), e0155282. doi:10.1371/journal.pone.0155282 | OSD-25 |
| Molecular effects of spaceflight in the mouse eye after space shuttle mission STS-135 | Theriot, C. A., Zanello, S. B., (2014). Molecular effects of spaceflight in the mouse eye after space shuttle mission STS-35. Gravitational and Space Research: publication of the American Society for Gravitational and Space Research, 2(1), 08-2014. | OSD-87 |
| Spaceflight Transcriptomes: Unique Responses to a Novel Environment | Paul, A. L., Zupanska, A. K., Ostrow, D. T., Zhang, Y., Sun, Y., Li, J. L., Shanker, S., Farmerie, W. G., Amalfitano, C. E., Ferl, R. J. (2012). Spaceflight Transcriptomes: Unique Responses to a Novel Environment, Astrobiology. 2012 Jan;12(1):40-56. doi: 10.1089/ast.2011.0696. | |
| Complete Genome Sequence of Klebsiella quasipneumoniae subsp. similipneumoniae Strain IF3SW-P1, Isolated from the International Space Station | Sushenko N S, Singh N K, Vellone D L, Tighe S W, Hedlund B P, Venkateswaran K, Mose D P (2022). Complete Genome Sequence of Klebsiella quasipneumoniae subsp. similipneumoniae Strain IF3SW-P1, Isolated from the International Space Station, Microbiol Resour Annonc. doi: 10.1128/mra.00476-22. Epub 2022 Jun 23. | OSD-470 |
| Spaceflight influences gene expression, photoreceptor integrity and oxidative stress-related damage in the murine retina | Overbey, E. G., da Silveira, W. A., Stanbouly, S., Nishiyama, N.C., Roque-Torres, G. D., Pecaut, M. J., Zawieja, D. C., Wang, C., Willey, J. S., Delp, M. D., Hardiman, G., Mao, X. W. | OSD-255 |
OSDR Publications in the News – 74
| Title | Description | Datasets |
|---|---|---|
| Advancing Science in Microgravity – Implications for Effective Therapies | Rangdal A, Munoz S, Ma C, De Lorenzo M S, Sherman L S (2025). Advancing Science in Microgravity – Implications for Effective Therapies, International Journal of Translational Science. https://doi.org/10.13052/ijts2246-8765.2025.001 | |
| Critical investments in bioregenerative life support systems for bioastronautics and sustainable lunar exploration | Porterfield D M, Tulodziecki D, Wheeler R, Cross M K D, Monje O, Rothschild L J, Barker R J, et al (2025). Critical investments in bioregenerative life support systems for bioastronautics and sustainable lunar exploration, NPJ Microgravity. doi: 10.1038/s41526-025-00518-4 | |
| LEAF – Lunar Effects on Agricultural Flora, An Artemis III Deployed Instrument | Jeseritz S J, Chamerlain C M, Escobar A C, Levy E R D, Jones M, Delong N, Sumler K, et al, (2025). LEAF – Lunar Effects on Agricultural Flora, An Artemis III Deployed Instrument, 54th International Conferece on Environmental Systems. | |
| Space Radiation Book Chapter: Health Impacts of Radiation in Space and Countermeasures | Tasoula A, Poignant F, Guarnieri J W, Schwertz H, Nelson G A, (2025). Space Radiation Book Chapter: Health Impacts of Radiation in Space and Countermeasures. | |
| Exploring plant responses to altered gravity for advancing space agriculture | Nie H, Zhou W, Zheng Z, Deng Y, Zhang W, Zhang M, Jiang Z, et al, (2025). Exploring plant responses to altered gravity for advancing space agriculture, Plant Communications. https://doi.org/10.1016/j.xplc.2025.101370 | |
| The utility of animal models to inform the next generation of human space exploration | Duporge I, Pereira T, Castiello de Obeso S, Ross J G B, Lee S J, Hindle A G, (2025). The utility of animal models to inform the next generation of human space exploration, Microgravity. https://doi.org/10.1038/s41526-025-00460-5 | |
| Satellite ISS Velocity Analysis in Earth Orbit | Lutz K, (2025). Satellite ISS Velocity Analysis in Earth Orbit, SctTech 2025, Atmospheric and Space Enrionments II Session. | |
| Astronaut proteomics: Japan leads the way for transformative studies in space | Tasoula A and Szewczyk N (2024). Astronaut proteomics: Japan leads the way for transformative studies in space, Proteomics. https://doi.org/10.1002/pmic.202300645 | |
| Gravitational and mechanical forces drive mitochondrial translation through the cell adhesion–FAK axis | Wakigawa T, Kimura Y, Mito M, Tsubaki T, Saito H, Khan A H, Yamamori T, et al (2024). Gravitational and mechanical forces drive mitochondrial translation through the cell adhesion–FAK axis, bioRxiv. https://doi.org/10.1101/2023.01.18.524628 | |
| Leveraging Geospatial Information to address Space Epidemiology | Sobel A L, Yeh K, Bradford E, Price C, Russell J, Olinger G, Grant S, et al (2024). Leveraging Geospatial Information to address Space Epidemiology, Arxiv. https://arxiv.org/ftp/arxiv/papers/2308/2308.07339.pdf | |
| 3t-seq: automatic gene expression analysis of single-copy genes, transposable elements, and tRNAs from RNA-seq data | Tabaro F, Boulard M, (2024). 3t-seq: automatic gene expression analysis of single-copy genes, transposable elements, and tRNAs from RNA-seq data, Briefings in Bioinformatics. https://doi.org/10.1093/bib/bbae467 | |
| Microbiology of human spaceflight: microbial responses to mechanical forces that impact health and habitat sustainability | Nickerson C A, McLean R J C, Barrila J, Yang J, Thornhill S G, Banken L L, Porterfield D M,et al, (2024). Microbiology of human spaceflight: microbial responses to mechanical forces that impact health and habitat sustainability, Microbiol Mol Biol Rev. https://journals.asm.org/doi/10.1128/mmbr.00144-23 | |
| Differential network analysis reveals the key role of the ECM-receptor pathway in α-particle-induced malignant transformation | Yan W, Hu W, Song Y, Liu X, Zhou Z, Li W, Cao Z, et al, (2024). Differential network analysis reveals the key role of the ECM-receptor pathway in α-particle-induced malignant transformation, Molecular Therapy Nucleic Acids. doi: 10.1016/j.omtn.2024.102260 | |
| Skeletal muscle-on-a-chip in microgravity as a platform for regeneration modeling and drug screening | Kim S, Ayan B, Shayan M, Rando T A, Huang N F, (2024). Skeletal muscle-on-a-chip in microgravity as a platform for regeneration modeling and drug screening, Stem Cell Reports. doi: 10.1016/j.stemcr.2024.06.010 | |
| A second space age spanning omics, platforms, and medicine across orbits | Mason C E, Green J, Adamopoulos K I, Afshin E E, Baechle J J, Basner M, Bailey S M, et al, (2024). A second space age spanning omics, platforms, and medicine across orbits, Nature. doi: 10.1038/s41586-024-07586-8 | |
| Astronaut omics and the impact of space on the human body at scale | Rutter L A, Cope H, MacKay M J, Herranz R, Das S, Ponomarev S A, Costes, S V, et al, (2024). Astronaut omics and the impact of space on the human body at scale, Nature Communications. doi: 10.1038/s41467-024-47237-0 | |
| Biological horizons: pioneering open science in the cosmos | Costes S V, Gentemann C L, Platts S H, Carnell L A, (2024). Biological horizons: pioneering open science in the cosmos, Nature Communications. doi: 10.1038/s41467-024-48633-2 | |
| Understanding how space travel affects the female reproductive system | Mathyk B, Imudia A N, Quaas A M, Halicigil C, Karouia F, Avci P, Nelson N G, et al, (2024). Understanding how space travel affects the female reproductive system, npj Women’s Health. doi: 10.1038/s44294-024-00009-z | |
| Domains of life sciences in spacefaring: What, where, and how to get involved | Berliner A J, Zezulka S, Hutchinson G A, Bertoldo S, Cockell C S, Arkin A P, (2024). Domains of life sciences in spacefaring: What, where, and how to get involved, npj Microgravity. DOI: 10.1038/s41526-024-00354-y | |
| How to obtain an integrated picture of the molecular networks involved in adaptation to microgravity in different biological systems? | Willis C R G, Calvaruso M, Angeloni D, Baatout S, Benchoua A, Bereiter-Hahn J, Bottai D, et al, (2024). How to obtain an integrated picture of the molecular networks involved in adaptation to microgravity in different biological systems?, npj microgravity. doi.org/10.1038/s41526-024-00395-3 | |
| Long-term space missions’ effects on the human organism: What we do know and what requires further research | Tomsia M, Cie la J, mieszek J, Florek S, Macionga A, Michalczyk K, Stygar D, (2024). Long-term space missions’ effects on the human organism: What we do know and what requires further research., Frontiers in Physiology. DOI 10.3389/fphys.2024.1284644 | |
| Metabolomic Profiling of the Secretome from Human Neural Stem Cells Flown into Space | Biancotti J C, Espinosa-Jeffrey A, (2024). Metabolomic Profiling of the Secretome from Human Neural Stem Cells Flown into Space, bioengineering. doi.org/10.3390/bioengineering11010011 | |
| Mitochondrial stress in the spaceflight environment | Rudolf A M and Hood W R, (2024). Mitochondrial stress in the spaceflight environment, Mitochondrion. doi.org/10.1016/j.mito.2024.101855 | |
| Nitrosative Stress in Astronaut Skeletal Muscle in Spaceflight | Blottner D, Moriggi M, Trautmann G, Furlan S, Block K, Gutsmann M, Torretta E, et al, (2024). Nitrosative Stress in Astronaut Skeletal Muscle in Spaceflight, antioxidants. doi.org/10.3390/antiox13040432 | |
| Omics Studies of Tumor Cells under Microgravity Conditions | Graf J, Herbert S, Wehland M, Corydon T J, Sahana J, Abdelfattah F, Wuest S L, et al, (2024). Omics Studies of Tumor Cells under Microgravity Conditions, International Journal of Molecular Sciences. doi.org/10.3390/ijms25020926 | |
| Procrustes is a machine-learning approach that removes cross-platform batch effects from clinical RNA sequencing data | Kotlov N, Shaposhnikov K, Tazearslan C, Chasse M, Baisangurov A, Podsvirova S, Fernandez D, et al, (2024). Procrustes is a machine-learning approach that removes cross-platform batch effects from clinical RNA sequencing data, communications biology. doi.org/10.1038/s42003-024-06020-z | |
| Roadmap for the next decade of plant programmed cell death research | Kacprzyk J, Burke R, Armengot L, Coppola M, Tattrie S B, Vahldick H, Bassham D C, et al, (2024). Roadmap for the next decade of plant programmed cell death research, New Phytologist. doi.org/10.1111/nph.19709 | |
| Simulated microgravity attenuates myogenesis and contractile function of 3D engineered skeletal muscle tissues | Ren Z, Ahn E H, Do M, Mair D B, Monemianesfahani A, Lee P H U, Kim D H, (2024). Simulated microgravity attenuates myogenesis and contractile function of 3D engineered skeletal muscle tissues, npj Microgravity. DOI: 10.1038/s41526-024-00353-z | |
| The use of RNA-seq for the study of Physiological Adaptations of Halophiles in Extreme Environments for Astrobiological Data Interpretation | Basu C and Perl S M, (2024). The use of RNA-seq for the study of Physiological Adaptations of Halophiles in Extreme Environments for Astrobiological Data Interpretation, Frontiers. DOI 10.3389/fspas.2024.1342694 | |
| Translating genetic findings to epigenetics: identifying the mechanisms associated with aging after high-radiation exposure on earth and in space | Ruprecht N A, Singhal S, Sens D, Singhal S K, (2024). Translating genetic findings to epigenetics: identifying the mechanisms associated with aging after high-radiation exposure on earth and in space, Frontiers In Public Health. DOI 10.3389/fpubh.2024.1333222 | |
| Caenorhabditis elegans in microgravity: an omics perspective | Scott A, Willis C R G, Muratani M, Higashitani A, Etheridge T, Szewczyk N J, Deane C S, (2023). Caenorhabditis elegans in microgravity: an omics perspective, iScience. https://doi.org/10.1016/j.isci.2023.107189 | |
| Big Data for a Small World: A Review on Databases and Resources for Studying Microbiomes | Sengupta P, Sivabalan S K M, Mahesh A, Palanikumar I, Baskaran D K K, and Raman K (2023). Big Data for a Small World: A Review on Databases and Resources for Studying Microbiomes, Journal of the Indian Institute of Science. | |
| Biological research and self-driving labs in deep space supported by artificial intelligence | Sanders L M , Scott R T , Yang J H , Qutub A A, Martin H G, Berrios D C, Hastings J J A , et al, (2023). Biological research and self-driving labs in deep space supported by artificial intelligence, nature machine intelligence. doi.org/10.1038/s42256-023-00618-4 | |
| Biomonitoring and precision health in deep space supported by artificial intelligence | Scott R T, Sanders L M, Antonsen E L, Hastings J J A, Park S M, Mackintosh G, Reynolds R J, et al, (2023). Biomonitoring and precision health in deep space supported by artificial intelligence, nature machine intelligence. doi.org/10.1038/s42256-023-00617-5 | |
| Current Knowledge about the Impact of Microgravity on Gene Regulation | Corydon T J, Schulz H, Richter P, Strauch S M, Böhmer M, Ricciardi D A, Wehland M, et al (2023). Current Knowledge about the Impact of Microgravity on Gene Regulation, Cells doi.org/10.3390/cells12071043 | |
| Database of space life investigations and information on spacefight plant biology | Wang S, Wang J, Zeng X, Wang T, Yu Z, Wei Y, Cai M, et al (2023). Database of space life investigations and information on spacefight plant biology, Planta. DOI: 10.1007/s00425-023-04213-0 | |
| Enhancing European capabilities for application of multi-omics studies in biology and biomedicine space research | Manzano A, Weging S, Bezdan D, Borg J, Cahill T, Carnero-Diaz E, Cope H, et al (2023). Enhancing European capabilities for application of multi-omics studies in biology and biomedicine space research, iScience. DOI: 10.1016/j.isci.2023.107289 | |
| Exploratory Tool for Radiation Exposure from Spaceflight: Rad-Bio-App | Ghosh D, Verma E, Ghosh R K, and Anderson T, (2023). Exploratory Tool for Radiation Exposure from Spaceflight: Rad-Bio-App, International Journal of Medical Science and clinical Invention. DOI:10.18535/ijmsci/v10i1.03 | |
| Exploring outer space biophysical phenomena via SpaceLID | Wang S, Wang T, Zeng X, Chu X, Zhuoma D, Zhao Y, and Chen Y Z, (2023). Exploring outer space biophysical phenomena via SpaceLID, Scientific Reports. DOI: 10.1038/s41598-023-44729-9 | |
| Lab Medicine in Space | Wiencek J R, Das S, Beheshti A, Crucian B E, Karouia F, Trudel G, and McMonigalm K A, (2023). Lab Medicine in Space, Clinical Chemistry. doi.org/10.1093/clinchem/hvad035 | |
| Metagenomic Methods for Addressing NASA’s Planetary Protection Policy Requirements on Future Missions: A Workshop Report | Green S J, Torok T, Allen J E, Eloe-Fadrosh E, Jackson S A, Jiang S C, Levine S S, et al (2023). Metagenomic Methods for Addressing NASA’s Planetary Protection Policy Requirements on Future Missions: A Workshop Report, Astrobiology. DOI: 10.1089/ast.2022.0044 | |
| Mitochondria Need Their Sleep: Redox, Bioenergetics, and Temperature Regulation of Circadian Rhythms and the Role of Cysteine-Mediated Redox Signaling, Uncoupling Proteins, and Substrate Cycles | Richardson R B, and Mailloux R J, (2023). Mitochondria Need Their Sleep: Redox, Bioenergetics, and Temperature Regulation of Circadian Rhythms and the Role of Cysteine-Mediated Redox Signaling, Uncoupling Proteins, and Substrate Cycles, Antioxidants. doi.org/10.3390/antiox12030674 | |
| Photosynthetic microorganisms, an overview of their biostimulant effects on plants and perspectives for space agriculture | Renaud C, Leys N, and Wattiez R (2023). Photosynthetic microorganisms, an overview of their biostimulant effects on plants and perspectives for space agriculture, Journal of Plant Interactions. DOI: 10.1080/17429145.2023.2242697 | |
| Plant Reactome Knowledgebase: empowering plant pathway exploration and OMICS data analysis | Gupta P, Elser J, Hooks E, D’Eustachio P, Jaiswal P, and Naithani S, (2023). Plant Reactome Knowledgebase: empowering plant pathway exploration and OMICS data analysis, Nucleic Acids Research. DOI: 10.1093/nar/gkad1052 | |
| RNA-Seq Alignment and Differential Expression Software Comparison | Munster S K, Nicholson S J, Uyhelji H A (2023). RNA-Seq Alignment and Differential Expression Software Comparison, Civil Aerospace Medical Institute (CAMI) Federal Aviation Administration. doi.org/10.21949/1524443 | |
| Spaceflight Induces Strength Decline in Caenorhabditis elegans | Soni P, Edwards H, Anupom T, Rahman M, Lesanpezeshki L, Blawzdziewicz J, Cope H, et al (2023). Spaceflight Induces Strength Decline in Caenorhabditis elegans, Cells. DOI: 10.3390/cells12202470 | |
| A Sankofian appraisal on how to maximize translatability of rodent space radiation/CNS studies to astronauts | Brittena R A, Sanford L D, Guo M L, Krishnan B, Emmett M R, Laiakis E C, (2022). A Sankofian appraisal on how to maximize translatability of rodent space radiation/CNS studies to astronauts,” The Health Risks of Extraterrestrial Environments (THREE). | |
| Alternative splicing diversifies the skeletal muscle transcriptome during prolonged spaceflight | Henrich M, Ha P, Wang Y, Ting K, Stodieck L, Soo C, Adams J S, et al (2022). Alternative splicing diversifies the skeletal muscle transcriptome during prolonged spaceflight, Skeletal Muscle. doi.org/10.1186/s13395-022-00294-9 | |
| Benchmark dose modeling of transcriptional data: a systematic approach to identify best practices for study designs used in radiation research | Stainforth R, Vuong N, Adam N, Kuo B, Wilkins R C, Yauk C, Beheshti B, et al, (2022). Benchmark dose modeling of transcriptional data: a systematic approach to identify best practices for study designs used in radiation research, International Journal of Radiation Biology. doi.org/10.1080/09553002.2022.2110300. | |
| Building the Space Omics Topical Team to boost European space researchers’ role in the international consortia redefining spaceflight-generated datasets | Herranz R, da Silveira W, Bezdan D, Giacomello S, and Szewczyk N (2022). Building the Space Omics Topical Team to boost European space researchers’ role in the international consortia redefining spaceflight-generated datasets, iScience. doi: 10.1016/j.isci.2022.10486 | |
| Clinical trial in a dish for space radiation countermeasure discovery. | Cao X, Weil M M, Wu J C, (2022). Clinical trial in a dish for space radiation countermeasure discovery, Life Sci Space Res. doi.org/10.1016/j.lssr.2022.05.006 | |
| Data Processing as Sharing Practice: Making Space Plant Biology at NASA GeneLab | Castano P, (2022). Data Processing as Sharing Practice: Making Space Plant Biology at NASA GeneLab, The 9th biennial conference of the Society for Philosophy of Science in Practice, pg 64-65. | |
| Dissociation of Bone Resorption and Formation in Spaceflight and Simulated Microgravity: Potential Role of Myokines and Osteokines? | Lau P, Vico L, and Rittweger J, (2022). Dissociation of Bone Resorption and Formation in Spaceflight and Simulated Microgravity: Potential Role of Myokines and Osteokines?, Biomedicines. doi.org/10.3390/biomedicines10020342 | |
| Estrogen receptor regulates phenotypic switching and proliferation of vascular smooth muscle cells through the NRF1-OMI-mitophagy signaling pathway under simulated microgravity | Jiang M, Liu Z, Shao J, Zhou J, Wang H, Song C, Li X, et al, (2022). Estrogen receptor regulates phenotypic switching and proliferation of vascular smooth muscle cells through the NRF1-OMI-mitophagy signaling pathway under simulated microgravity, Frontiers. doi: 10.3389/fphys.2022.1039913 | |
| From Cultured Vascular Cells to Vessels: The Cellular and Molecular Basis of Vascular Dysfunction in Space | Locatelli L, Castiglioni S, Maier J A M, (2022). From Cultured Vascular Cells to Vessels: The Cellular and Molecular Basis of Vascular Dysfunction in Space, Front Bioeng Biotechnol. doi: 10.3389/fbioe.2022.862059 | |
| Integrating bioinformatic strategies in spatial life science research | Hao Y, Lu L, Liu A, Lin X, Xiao L, Kong X, Li K, et al (2022). Integrating bioinformatic strategies in spatial life science research, Briefings in Bioinformatics. doi.org/10.1093/bib/bbac415 | |
| Inter-agency perspective: Translating advances in biomarker discovery and medical countermeasures development between terrestrial and space radiation environments | DiCarlo A L, Carnell L S, Rios C I, Prasanna P G, (2022). Inter-agency perspective: Translating advances in biomarker discovery and medical countermeasures development between terrestrial and space radiation environments, Life Sciences in Space Research. doi.org/10.1016/j.lssr.2022.06.004 | |
| Latest knowledge about changes in the proteome in microgravity | Schulz H, Strauch S M, Richter P, Wehland M, Krüger M, Sahana J, Corydon T J, et al, (2022). Latest knowledge about changes in the proteome in microgravity, Expert Review of Proteomics. doi.org/10.1080/14789450.2022.2030711 | |
| Meta-analysis of health research data from greater than three months International Space Station missions | Kunitskaya A, PiretJ M, Buckley N, Low-Décarie E (2022). Meta-analysis of health research data from greater than three months International Space Station missions, Acta Astronautica. doi.org/10.1016/j.actaastro.2022.09.019 | |
| Multiscale modeling in the framework of biological systems and its potential for spaceflight biology studies | Millar-Wilson A, Ward Ó, Duffy E, Hardiman G, (2022). Multiscale modeling in the framework of biological systems and its potential for spaceflight biology studies, iScience. doi: 10.1016/j.isci.2022.105421 | |
| Physiological adaptations affecting drug pharmacokinetics in space: what do we really know? A critical review of the literature. | Russo C D, Bandiera T, Monici M, Surdo L, Yip V L M, Wotring V, Morbidelli L, (2022). Physiological adaptations affecting drug pharmacokinetics in space: what do we really know? A critical review of the literature, British Journal of Pharmacology. DOI: 10.22541/au.162636523.37754419/v1 | |
| Plants in Microgravity: Molecular and Technological Perspectives | Baba A I, Mir M Y, Riyazuddin R, Cséplo A, Rigó G, and Fehér A (2022). Plants in Microgravity: Molecular and Technological Perspectives, International Journal of Molecular Sciences. doi.org/10.3390/ijms2318105487 | |
| Rare diseases and space health: Optimizing synergies from scientific questions to care | Puscas M, Martineau G, Bhella G, Bonnen P E, Carr P, Lim R, Mitchell J, et al, (2022). Rare diseases and space health: Optimizing synergies from scientific questions to cares, NPJ Microgravity. doi: 10.1038/s41526-022-00224-5 | |
| Routine omics collection is a golden opportunity for European human research in space and analog environments | Cope H, Willis C R G, MacKay M J, Rutter L A, Toh L S, Williams P M, Herranz R, et al, (2022). Routine omics collection is a golden opportunity for European human research in space and analog environments, Patterns. doi.org/10.1016/j.patter.2022.100550 | |
| The Biological Problems of Space Travel | Reid M, (2022). The Biological Problems of Space Travel, Ideas Magazine. | |
| The Fight against Cancer by Microgravity: The Multicellular Spheroid as a Metastasis Model | Grimm D, Schulz H, Krüger M, Cortés-Sánchez J L, Egli M, Kraus A, Sahana J, et al, (2022). The Fight against Cancer by Microgravity: The Multicellular Spheroid as a Metastasis Model, International Journal of Molecular Sciences. doi.org/10.3390/ijms23063073. | |
| The mitochondrial proteomic changes of rat hippocampus induced by 28-day simulated microgravity | Ji G, Chang H, Yang M, Chen H, Wang T, Liu X, Lv K, et al, (2022). The mitochondrial proteomic changes of rat hippocampus induced by 28-day simulated microgravity, PLOS ONE. doi.org/10.1371/journal. pone.0265108. | |
| Validating Causal Diagrams of Human Health Risks for Spaceflight: An Example Using Bone Data from Rodents | Reynolds R J, Scott R T, Turner R T, Iwaniec U T, Bouxsein M L, Sanders L M, and Antonsen E L, (2022). Validating Causal Diagrams of Human Health Risks for Spaceflight: An Example Using Bone Data from Rodents, Biomedicines. doi.org/10.3390/biomedicines10092187 | |
| A Meta-Analysis of the Effects of High-LET Ionizing Radiations in Human Gene Expression | Michalettou T D, Michalopoulos I, Costes S V, Hellweg C E, Hada M, and Georgakilas A G, (2021). A Meta-Analysis of the Effects of High-LET Ionizing Radiations in Human Gene Expression, Life. doi.org/10.3390/ life11020115 | |
| Animal Models for Radiotherapy Research: All (Animal) Models Are Wrong but Some Are Useful | Butterworth K T, and Williams J P, (2021). Animal Models for Radiotherapy Research: All (Animal) Models Are Wrong but Some Are Useful, Cancers. doi.org/10.3390/cancers 13061319 | |
| Animal models, open science, & space-omics | Neff E P, (2021). Animal models, open science, & space-omics, Lab Animal. doi.org/10.1038/s41684-021-00776-1 | |
| Cyanobacteria and microalgae in supporting human habitation on Mars | Mapstone L J, Leite M N, Purton S, Crawford I A, Dartnell L, (2021). Cyanobacteria and microalgae in supporting human habitation on Mars, Biotechnology Advances. doi.org/10.1016/j.biotechadv.2022.107946 | OSD-265 |
| Genomic Changes Driven by Radiation-Induced DNA Damage and Microgravity in Human Cells | Beheshti A, McDonald J T, Hada M, Takahashi A, Mason C E, and Mognato M, (2021). Genomic Changes Driven by Radiation-Induced DNA Damage and Microgravity in Human Cells, International Journal of Molecular Sciences. doi.org/10.3390/ijms221910507 | |
| Conducting Plant Experiments in Space and on the Moon | Shymanovich T and Kiss J Z, (2022). Conducting Plant Experiments in Space and on the Moon, Plant Gravitropism Methods in Molecular Biology. doi: 10.1007/978-1-0716-1677-2_12 |
Student Publications – 15
| Title | Description | Datasets |
|---|---|---|
| Spaceflight-Induced Physiological Changes: A Computational Comparative Analysis of Drosophila and C. elegans | Mathew A (2025). Spaceflight-Induced Physiological Changes: A Computational Comparative Analysis of Drosophila and C. elegans. [Bachelor of Science Thesis, Honors Tutorial College Ohio University]. | OSD-514 |
| Methods To Develop An 8-Oxog Base Modification Classifier For Direct-Dna Nanopore Sequencing | Arikatla M R (2024). Methods To Develop An 8-Oxog Base Modification Classifier For Direct-Dna Nanopore Sequencing. [Master’s Thesis, Weill Cornell Graduat School of Medical Sciences.] | OSD-255 |
| Detecting de novo Insertions of Transposable Elements in the Human Genome | McConnell J (2024). Detecting de novo Insertions of Transposable Elements in the Human Genome. [Master’s Thesis, The University of Adelaid. | OSD-84 |
| The Architecture of Microgravity Environments | Soto R R, (2024). The Architecture of Microgravity Environments. [Master’s Thesis, Carleton University. DOI: https://doi.org/10.22215/etd/2024-16005 | |
| Differential Gene Expression Analysis of Rodent Mammary Tissue Reveals Dysregulation of Greb1 and an Age-Dependent Response to Spaceflight | Arnold C (2023). Differential Gene Expression Analysis of Rodent Mammary Tissue Reveals Dysregulation of Greb1 and an Age-Dependent Response to Spaceflight. [Master’s Thesis, San Jose State University]. DOI: https://doi.org/10.31979/etd.53cj-bbgq | OSD-511 |
| Select Pathways Revealed in A. Thaliana During Spaceflight Via Meta-Analysis of National Aeronautics and Space Administration Genelab Data | Baham, Z T, (2023). Select Pathways Revealed in A. Thaliana During Spaceflight Via Meta-Analysis of National Aeronautics and Space Administration Genelab Data. [Master’s Thesis, Louisiana Tech University]. | OSD-7, OSD-38, OSD-120, OSD-205, OSD-213, OSD-251, OSD-314, OSD-469 |
| Characterizing the relative biologic effectiveness following clinical and space-relevant ionizing radiation exposures and exploring curcumin nanoparticles as effective radiological countermeasures | Evans A C, (2022). Characterizing the relative biologic effectiveness following clinical and space-relevant ionizing radiation exposures and exploring curcumin nanoparticles as effective radiological countermeasures. [Doctoral thesis, University of California Davis]. | |
| Computational techniques for simulation and design of a biological sample irradiation chamber | Giunta E, (2022). Computational techniques for simulation and design of a biological sample irradiation chamber. [Master’s Thesis, Kansas State University]. | |
| Differential Gene Expression Analysis of Zebrafish Embryos Exposed to Simulated Microgravity and Insights into Cellular Effects | Lien N, (2022). Differential Gene Expression Analysis of Zebrafish Embryos Exposed to Simulated Microgravity and Insights into Cellular Effects. [Master’s Projects, San Jose State University]. Master’s Thesis and Graduate Research. | OSD-373, OSD-289 |
| Effects of Aeration on Soybean Plant Growth in Lunar and Martian Regolith | Josh Bailey, Kyra Keenan, Alessandro Paz, Riya Dharmendra Raj, Madelyn Whitaker, Brian Wodetzki, Autumn Wuebben, (2022). Effects of Aeration on Soybean Plant Growth in Lunar and Martian Regolith. [Purdue Interplanetary and Space Agriculture, Undergraduate Division]. | |
| The role of osteocytes in mechanical unloading and age-induced osteopenia | Uda Y, (2022). The role of osteocytes in mechanical unloading and age-induced osteopenia. [Boston University]. Doctoral dissertation. | OSD-50, OSD-107 |
| An Examination of Bone Loss During Space Travel with Differential Gene Expression Analysis | Vo C, (2021). An Examination of Bone Loss During Space Travel with Differential Gene Expression Analysis. [Master’s Projects, San Jose Sate University]. Master’s Theses and Graduate Research. DOI: https://doi.org/10.31979/etd.an9m-wtkd | OSD-241 |
| Effects Of Microgravity and Partial Gravity and the Influence of Photostimulation on Plant Adaptation to Spaceflight | Calvo A V, (2021). Effects of Microgravity and Partial Gravity and the Influence of Photostimulation on Plant Adaptation to Spaceflight. [Doctoral thesis, Universidad Autónoma de Madrid]. CSIC – Centro de Investigaciones Biológicas Margarita Salas (CIB). http://hdl.handle.net/10261/253186 | OSD-251, OSD-313, OSD-314 |
| Spaceflight and Differential Gene Expression Analysis of Mice Quadriceps Exposed to Microgravity | Nguyen T, (2021). Spaceflight and Differential Gene Expression Analysis of Mice Quadriceps Exposed to Microgravity. [Master’s Projects, San Jose Sate University]. Master’s Theses and Graduate Research. DOI: https://doi.org/10.31979/etd.4tt8-8a9h | OSD-103 |
| Spaceflight and the Differential Gene Expression of Human Stem Cell-Derived Cardiomyocytes | Zhu E, (2021). Spaceflight and the Differential Gene Expression of Human Stem Cell-Derived Cardiomyocytes. [Master’s Projects, San Jose Sate University]. Master’s Theses and Graduate Research. DOI: https://doi.org/10.31979/etd.ub3z-s62y | OSD-258 |